Template:Epidural Abscess Treatment
- Target Staph, Strep, and Gram-negative bacilli[1]
- Vancomycin 15-20mg/kg BID + 500mg (7.5mg/kg) q6 hrs + (Cefotaxime or standard dosing or Ceftazidime)
- Ceftazidime is preferred if pseudomonas is considered likely
- Can substitute Nafcillin or Oxacillin for Vancomycin if not MRSA
Treat for 6-8 weeks
Pediatric
- Vancomycin 15mg/kg IV q6hrs + Ceftriaxone 50-75mg/kg IV daily (max 2g) + Metronidazole 7.5mg/kg IV q6hrs (max 500mg)
- Treat for 6-8 weeks
- ↑ Rigamonti D. et al. Spinal epidural abscess: contemporary trends in etiology, evaluation, and management. Surg Neurol 1999; 52:189-96