High-output heart failure: Difference between revisions

(Expanded with concise EM-focused content: warm extremities distinction, common causes, evaluation, treat underlying cause, disposition)
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==Background==
==Background==
*High metabolic state or shunting of blood increasing cardiac demand
*High-output heart failure occurs when cardiac output is elevated but cannot meet the body's increased metabolic demands
*Unlike typical heart failure, the heart itself may be structurally normal initially
*Extremities are typically '''warm and well-perfused''' (distinguishing feature from low-output heart failure)
*Can progress to low-output failure if untreated


==Clinical Features==
==Clinical Features==
*Dyspnea, fatigue, [[Bilateral pedal edema|peripheral edema]]
*Dyspnea, fatigue, exercise intolerance
*Warm and well-perfused extremities
*Warm, well-perfused extremities (unlike cold/clammy in low-output failure)
*Bounding pulse with wide pulse pressure
*Bounding pulse with '''wide pulse pressure'''
*Peripheral edema, pulmonary congestion
*May have signs of underlying cause (goiter, AV fistula bruit, pallor)


==Differential Diagnosis==
==Differential Diagnosis==
{{Template:High-output heart failure DDX}}
{{Template:High-output heart failure DDX}}
===Common Causes===
*'''Severe [[anemia]]''' (Hgb <5-7 g/dL)
*'''[[Hyperthyroidism]] / [[thyroid storm]]'''
*'''AV fistula''' (dialysis access, traumatic, congenital)
*'''[[Sepsis]]'''
*'''Paget's disease of bone'''
*'''[[Thiamine]] deficiency (wet [[beriberi]])'''
*'''Pregnancy'''
*'''Cirrhosis'''
*'''Morbid obesity'''


==Evaluation==
==Evaluation==
*[[CBC]]: anemia
*[[TSH]]: hyperthyroidism
*[[BNP]]: elevated (not as reliable for distinguishing high vs. low output)
*[[Thiamine]] level if suspected deficiency (alcoholism, malnutrition)
*[[ECG]]: tachycardia, may show strain pattern
*[[CXR]]: cardiomegaly, pulmonary congestion
*[[Echocardiography]]: elevated EF (early), dilated chambers; eventually may show reduced EF
*Assess for AV fistula bruit (dialysis patients)


==Management==
==Management==
*'''Treat underlying cause''' — this is definitive management
**Anemia: transfuse
**Hyperthyroidism: beta-blockers, antithyroid medications
**Sepsis: antibiotics, source control
**Thiamine deficiency: IV [[thiamine]] 500 mg before glucose
**AV fistula: may need ligation if causing heart failure
*Standard heart failure management for acute symptoms: diuretics for congestion, oxygen
*Avoid excessive volume removal in AV fistula-related heart failure


==Disposition==
==Disposition==
*Admit
*Admit: new diagnosis of heart failure, hemodynamic compromise, severe underlying cause (thyroid storm, sepsis, severe anemia)
*Discharge: mild symptoms with correctable cause identified and treated (e.g., anemia transfused, thyroid medication adjusted) with close follow-up


==See Also==
==See Also==
*[[Heart failure]]
*[[Congestive heart failure]]
*[[In-Training Exam Review]]
*[[Hyperthyroidism]]
*[[Anemia]]
*[[Beriberi]]


==References==
==References==
<References/>
<references/>


[[Category:Cardiology]]
[[Category:Cardiology]]

Revision as of 00:37, 21 March 2026

Background

  • High-output heart failure occurs when cardiac output is elevated but cannot meet the body's increased metabolic demands
  • Unlike typical heart failure, the heart itself may be structurally normal initially
  • Extremities are typically warm and well-perfused (distinguishing feature from low-output heart failure)
  • Can progress to low-output failure if untreated

Clinical Features

  • Dyspnea, fatigue, exercise intolerance
  • Warm, well-perfused extremities (unlike cold/clammy in low-output failure)
  • Bounding pulse with wide pulse pressure
  • Peripheral edema, pulmonary congestion
  • May have signs of underlying cause (goiter, AV fistula bruit, pallor)

Differential Diagnosis

Common Causes

Evaluation

  • CBC: anemia
  • TSH: hyperthyroidism
  • BNP: elevated (not as reliable for distinguishing high vs. low output)
  • Thiamine level if suspected deficiency (alcoholism, malnutrition)
  • ECG: tachycardia, may show strain pattern
  • CXR: cardiomegaly, pulmonary congestion
  • Echocardiography: elevated EF (early), dilated chambers; eventually may show reduced EF
  • Assess for AV fistula bruit (dialysis patients)

Management

  • Treat underlying cause — this is definitive management
    • Anemia: transfuse
    • Hyperthyroidism: beta-blockers, antithyroid medications
    • Sepsis: antibiotics, source control
    • Thiamine deficiency: IV thiamine 500 mg before glucose
    • AV fistula: may need ligation if causing heart failure
  • Standard heart failure management for acute symptoms: diuretics for congestion, oxygen
  • Avoid excessive volume removal in AV fistula-related heart failure

Disposition

  • Admit: new diagnosis of heart failure, hemodynamic compromise, severe underlying cause (thyroid storm, sepsis, severe anemia)
  • Discharge: mild symptoms with correctable cause identified and treated (e.g., anemia transfused, thyroid medication adjusted) with close follow-up

See Also

References