Erythema infectiosum: Difference between revisions
m (Mholtz moved page Erythema Infectiosum (Fifth disease) to Erythema infectiosum (fifth disease)) |
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==Background== | ==Background== | ||
*Caused by Parvovirus B19 | *Caused by Parvovirus B19 | ||
**Infection in pregnancy can → [[Hydrops fetalis]] and fetal loss | **Infection in pregnancy can → [[Hydrops fetalis]], fetal anemia, and fetal loss | ||
**May precipitate aplastic crisis in patients with sickle cell disease | **May precipitate aplastic crisis in patients with sickle cell disease | ||
Revision as of 21:34, 27 December 2015
Background
- Caused by Parvovirus B19
- Infection in pregnancy can → Hydrops fetalis, fetal anemia, and fetal loss
- May precipitate aplastic crisis in patients with sickle cell disease
Clinical Features
- Initially mild URI-type symptoms
- "Slapped cheeks" rash
- Abrupt appearance on day 3-4
- Spares eyelids and chin
- Lasts 4-5 days
- Abrupt appearance on day 3-4
- Macular erythema develops on trunk/limbs 2 days after appearance of facial rash
- distinctive aspect of rash: faces with central clearing, giving a reticulated or lacy appearance
- May last 1 week
- Rash may recur within 3 week period
- Associated symptoms include fever, HA, sore throat, cough, coryza, N/V
Differential Diagnosis
Pediatric Rash
- Atopic dermatitis
- Bed bugs
- Contact dermatitis
- Drug rash
- Erythema infectiosum (Fifth disease)
- Hand-foot-and-mouth disease
- Henoch-schonlein purpura (HSP)
- Herpangina
- Herpes simplex virus (HSV)
- Infectious mononucleosis
- Meningitis
- Measles
- Molluscum contagiosum
- Roseola infantum
- Rubella (German measles)
- Scabies
- Scarlet fever
- Smallpox
- Varicella (Chickenpox)
Diagnosis
- Clinical diagnosis, based on history and physical exam
Management
- Symptomatic
Disposition
- Discharge
- (Admit if aplastic crisis)
Complications
- Symmetric Polyarthropathy
- Myocarditis
- Pericarditis
- Glomerulonephritis
- Focal Glomerulosclerosis