Typhus: Difference between revisions
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* Painless eschar at inoculation site imp clue | * Painless eschar at inoculation site imp clue | ||
* Camping, hiking in grassy/ scrub area | * Camping, hiking in grassy/ scrub area | ||
* Regional | * Regional lymphadenopathy, rash | ||
==Differential Diagnosis== | ==Differential Diagnosis== | ||
Revision as of 13:24, 19 May 2016
Background
- Not to be confused with typhoid fever, a distinct disease caused by a different genera of bacteria
- Any of several similar diseases caused by Rickettsia bacteria (e.g. Rickettsia prowazekii, )
Clinical Features
- Fever, headache, myalgias[1]
- Transmitted by arthropods/ ticks
- Painless eschar at inoculation site imp clue
- Camping, hiking in grassy/ scrub area
- Regional lymphadenopathy, rash
Differential Diagnosis
Fever in traveler
- Normal causes of acute fever!
- Malaria
- Dengue
- Leptospirosis
- Typhoid fever
- Typhus
- Viral hemorrhagic fevers
- Chikungunya
- Yellow fever
- Rift valley fever
- Q fever
- Amebiasis
- Zika virus
Diagnosis
- leukopenia, thrombocytopenia
- Usually clinically
Treatment
- Tetracycline
- Chloramphenicol may be an alternative, though associated with higher morbidity
- Confirm serologically, not useful in acute phase