Sepsis (peds): Difference between revisions
(Created page with "==Background== *Neonatal Sepsis **Early onset ***First few days of life ***Fulminant, assoc w/ maternal or perinatal risk factors ***Septic shock and neutropenia are more common ...") |
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==Disposition== | ==Disposition== | ||
*Admit all neonates | *Admit all neonates | ||
==See Also== | |||
[[Pediatric Fever]] | |||
==Source== | ==Source== | ||
Revision as of 19:14, 1 March 2012
Background
- Neonatal Sepsis
- Early onset
- First few days of life
- Fulminant, assoc w/ maternal or perinatal risk factors
- Septic shock and neutropenia are more common
- Late onset
- Occurs after 1wk of age
- Gradual
- Meningitis more likely
- Early onset
Diagnosis
- Temperature instability (temp >100.4)
- CNS dysfunction
- Respiratory distress
- Feeding disturbance
- Jaundice
- Rash
- Lethargy, irritability, sz
- Apnea, tachypnea, grunting
- Vomiting, poor PO, gastric distention, diarrhea
Work-Up
- CBC
- UA/Ucx
- CXR
- CSF
- Blood Cx
Treatment
- Neonatal
- Ampicillin 50mg/kg + gentamicin 2.5mg/kg + acyclovir
- If gram-negative strongly suspected replace gent w/ cefotaxime or ceftaz
- Have better CNS penetration
- If gram-negative strongly suspected replace gent w/ cefotaxime or ceftaz
- Ampicillin 50mg/kg + gentamicin 2.5mg/kg + acyclovir
Disposition
- Admit all neonates
See Also
Source
Tintinalli