Carbon disulfide toxicity: Difference between revisions

m (Rossdonaldson1 moved page Carbon Disulfide to Carbon disulfide toxicity)
(Text replacement - "==Treatment==" to "==Management==")
 
(3 intermediate revisions by 3 users not shown)
Line 4: Line 4:
*Also a metabolite of drug Disulfiram
*Also a metabolite of drug Disulfiram


==Mechanism of Toxicity==
===Mechanism of Toxicity===
*Disruption of enzymes and metabolic pathways including in the CNS
*Disruption of enzymes and metabolic pathways including in the CNS


Line 12: Line 12:
*CNS depression
*CNS depression


==Diagnosis==
==Differential Diagnosis==
 
==Evaluation==
*Based on clinical history and presenting signs and symptoms
*Based on clinical history and presenting signs and symptoms


==Treatment==
==Management==
*Decontaminate
*Decontaminate
*Consider activated charcoal for oral ingestions
*Consider [[activated charcoal]] for oral ingestions
*No specific antidotes available
*No specific antidotes available
==Disposition==


==See Also==
==See Also==


==References==
==References==
Olson, K. Poisoning and Drug Overdose, 1999.
*Olson, K. Poisoning and Drug Overdose, 1999.
 
[[Category:Toxicology]]

Latest revision as of 12:15, 10 December 2017

Background

  • Organic Solvent
  • Precursor in rubber industry
  • Also a metabolite of drug Disulfiram

Mechanism of Toxicity

  • Disruption of enzymes and metabolic pathways including in the CNS

Clinical Features

  • Eye irritation
  • Skin irritation
  • CNS depression

Differential Diagnosis

Evaluation

  • Based on clinical history and presenting signs and symptoms

Management

  • Decontaminate
  • Consider activated charcoal for oral ingestions
  • No specific antidotes available

Disposition

See Also

References

  • Olson, K. Poisoning and Drug Overdose, 1999.