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| {{Navbox
| | ==1st Generation== |
| | name = Cell wall disruptive antibiotics
| | *Skin and soft tissue infections (why is agent of choice before generalized symptoms) |
| | title = [[Antibiotics]]
| | *[[EBQ:Cephalosporin Cross-reactivity|Cross-reactivity of PCN]] allergy <10% |
| | state = {{{state|autocollapse}}}
| |
| |listclass = hlist
| |
| | groupstyle = background:PowderBlue;
| |
|
| |
|
| |group1 = Intracellular
| | ==2nd Generation== |
| |list1 =
| | *Intestinal [[anaerobes]] (why is agent of choice for colorectal sx) |
| * ([[Fosfomycin]]) | | *Largely displaced by 3rd gen agents |
| * ([[Cycloserine]])
| |
| * ([[Bacitracin]]) | |
|
| |
|
| | group2 = Glycopeptide
| | ==3rd Generation== |
| | list2 =
| | *Drug of choice for serious infections due to: |
| * [[Vancomycin]] | | **[[Klebsiella]] |
| * [[Teicoplanin]] ([[Dalbavancin]]) | | **[[Enterobacter]] |
| * [[Ramoplanin]] | | **Proteus |
| | **[[Haemophilus]] |
| | *[[Gonorrhea]] |
| | *[[Lyme Disease]] |
| | *[[Meningitis]] (+ [[vanc]] and [[ampicillin]]) |
| | *[[Pseudomonas]] meningitis (+ AG) |
|
| |
|
| | ==4th Generation== |
| | *Resistant, nosocomial infections |
|
| |
|
| |group3 = β-lactams
| | {{Clinically Utilized Antibiotics}} |
| |list3 = {{Navbox subgroup
| |
| | groupstyle = background:PowderBlue;
| |
|
| |
|
| | group1 = Penicillins
| | ==See Also== |
| | list1 = {{Navbox subgroup
| | *[[Antibiotics (Main)]] |
| | groupstyle = background:PowderBlue;
| | *[[Cephalosporin Cross-reactivity]] |
|
| |
|
| | group1 = Extended spect.
| | ==References== |
| | list1 =
| | <references/> |
| * ''Aminopenicillins:'' [[Amoxicillin]]
| | Goodman & Gilman's Pharmacology |
| * [[Ampicillin]]
| |
|
| |
|
| *''Carboxypenicillins:'' [[Carbenicillin]] ([[Carindacillin]])
| | [[Category:Pharmacology]] |
| * [[Ticarcillin]]
| | [[Category:ID]] |
| * [[Temocillin]]
| |
| | |
| *''Ureidopenicillins:'' [[Azlocillin]]
| |
| * [[Piperacillin]]
| |
| * [[Mezlocillin]]
| |
| | |
| *''other:'' [[Mecillinam]] ([[Pivmecillinam]])
| |
| * [[Sulbenicillin]]
| |
| | |
| | group2 = Narrow spect.
| |
| | list2 = {{Navbox subgroup
| |
| | groupstyle = background-color: PowderBlue
| |
| | |
| | group1 = β-lactamase sensitive
| |
| | list1 =
| |
| * [[Benzylpenicillin|Benzylpenicillin (G)]]: [[Clometocillin]]
| |
| * [[Benzathine benzylpenicillin]]
| |
| * [[Procaine benzylpenicillin]]
| |
| * [[Azidocillin]]
| |
| * [[Penamecillin]] <BR>
| |
| | |
| * [[Phenoxymethylpenicillin|Phenoxymethylpenicillin (V)]] [[Propicillin]]
| |
| * [[Benzathine phenoxymethylpenicillin]]
| |
| * [[Pheneticillin]]
| |
| | |
| |group2 = β-lactamase resistant
| |
| |list2 =
| |
| * [[Cloxacillin]] ([[Dicloxacillin]]
| |
| * [[Flucloxacillin]])
| |
| * [[Oxacillin]]
| |
| * [[Meticillin]]
| |
| * [[Nafcillin]]
| |
| | |
| }}
| |
| | |
| }}
| |
| | groupstyle = background-color: PowderBlue
| |
| | group2 = Penems
| |
| | list2 =
| |
| * [[Faropenem]]
| |
| | |
| | group3 = Carbapenems
| |
| | list3 =
| |
| * [[Biapenem]]
| |
| * [[Ertapenem]]
| |
| * ''[[antipseudomonal]]'' ([[Doripenem]]
| |
| * [[Imipenem]]
| |
| * [[Meropenem]])
| |
| * [[Panipenem]]
| |
| | groupstyle = background-color: PowderBlue
| |
| | |
| | group4= Cephalosporins/Cephamycins<BR>(cephems)
| |
| | list4= {{Navbox subgroup
| |
| | groupstyle = background-color: PowderBlue
| |
| | |
| | group1 = 1st ([[Proteus mirabilis|P]][[Escherichia coli|Ec]][[Klebsiella pneumoniae|K]])
| |
| | list1 =
| |
| * [[Cefazolin]]
| |
| * [[Cefacetrile]]
| |
| * [[Cefadroxil]]
| |
| * [[Cephalexin]]
| |
| * [[Cefaloglycin]]
| |
| * [[Cefalonium]]
| |
| * [[Cefaloridine]]
| |
| * [[Cefalotin]]
| |
| * [[Cefapirin]]
| |
| * [[Cefatrizine]]
| |
| * [[Cefazedone]]
| |
| * [[Cefazaflur]]
| |
| * [[Cefradine]]
| |
| * [[Cefroxadine]]
| |
| * [[Ceftezole]]
| |
| | |
| | group2= 2nd ([[Haemophilus influenzae|H]][[Enterobacter aerogenes|E]][[Neisseria|N]])
| |
| | list2=
| |
| * [[Cefaclor]]
| |
| * [[Cefamandole]]
| |
| * [[Cefminox]]
| |
| * [[Cefonicid]]
| |
| * [[Ceforanide]]
| |
| * [[Cefotiam]]
| |
| * [[Cefprozil]]
| |
| * [[Cefbuperazone]]
| |
| * [[Cefuroxime]]
| |
| * [[Cefuzonam]]
| |
| * ''[[cephamycin]]'' ([[Cefoxitin]]
| |
| * [[Cefotetan]]
| |
| * [[Cefmetazole]])
| |
| * ''[[carbacephem]]'' ([[Loracarbef]])
| |
| | |
| | group3= 3rd
| |
| | list3=
| |
| * [[Cefixime]]
| |
| * [[Ceftriaxone]]
| |
| * ''[[antipseudomonal]]'' ([[Ceftazidime]]
| |
| * [[Cefoperazone]])
| |
| * [[Cefcapene]]
| |
| * [[Cefdaloxime]]
| |
| * [[Cefdinir]]
| |
| * [[Cefditoren]]
| |
| * [[Cefetamet]]
| |
| * [[Cefmenoxime]]
| |
| * [[Cefodizime]]
| |
| * [[Cefotaxime]]
| |
| * [[Cefpimizole]]
| |
| * [[Cefpiramide]]
| |
| * [[Cefpodoxime]]
| |
| * [[Cefsulodin]]
| |
| * [[Cefteram]]
| |
| * [[Ceftibuten]]
| |
| * [[Ceftiolene]]
| |
| * [[Ceftizoxime]]
| |
| * ''[[oxacephem]]'' ([[Flomoxef]]
| |
| | |
| | group4= 4th (antipseudomonal)
| |
| | list4=
| |
| * [[Cefepime]]
| |
| * [[Cefozopran]]
| |
| * [[Cefpirome]]
| |
| * [[Cefquinome]]
| |
| | |
| | group5= 5th
| |
| | list5=
| |
| * [[Ceftobiprole]]
| |
| * [[Ceftaroline fosamil]]
| |
| | |
| }}
| |
| | |
| | group5 = Monobactams
| |
| | list5 =
| |
| * [[Aztreonam]]
| |
| * [[Tigemonam]]
| |
| * [[Carumonam]]
| |
| * [[Nocardicin A]]
| |
| | |
| | group6 = β-lactamase inh.
| |
| | list6 =
| |
| * ''[[penam]]'' ([[Sulbactam]]
| |
| * [[Tazobactam]])
| |
| * ''[[clavam]]'' ([[Clavulanic acid]])
| |
| | |
| | group7 = Combinations
| |
| | list7 =
| |
| * [[Amoxicillin/clavulanic acid]]
| |
| * [[Imipenem/cilastatin]]
| |
| * [[Ampicillin/flucloxacillin]]
| |
| * [[Ampicillin/sulbactam]] ([[Sultamicillin]])
| |
| * [[Piperacillin/tazobactam]]
| |
| | |
| }}
| |
| | |
| | group8 = Other
| |
| | list8 =
| |
| * ''[[polymyxin]]s/[[detergent]]'' ([[Colistin]]
| |
| * [[Polymyxin B]])
| |
| * ''[[depolarizing]]'' ([[Daptomycin]])
| |
| * ''hydrolyze NAM-NAG'' ([[Lysozyme]])
| |
| * [[Gramicidin]]
| |
| * [[Isoniazid]]
| |
| | |
| | |
| }}<noinclude>
| |
| {{collapsible option}}
| |
| | |
| </noinclude>
| |
| | |
| [[Category:Drugs]] | |
