Template:Botulism treatment: Difference between revisions

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If suspect possible bioterrorism, contact CDC +1-770-488-7100
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===Supportive Care===
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===Supportive Care=== <!--T:1-->
 
<!--T:2-->
*Early ventilatory support
*Early ventilatory support
**Consider intubation when vital capacity <30% predicted or <12cc/kg
**Consider intubation when vital capacity <30% predicted or <12cc/kg
*Wound Managment
*Wound Managment
**Early wound debreedment with surgical consult.
**Early wound debreedment with surgical consult.
**Also exclude [[Necrotizing fasciitis]] and coverage with same broad antibiotic coverage
**Also exclude [[Special:MyLanguage/Necrotizing fasciitis|Necrotizing fasciitis]] and coverage with same broad antibiotic coverage
===Foodborne Botulism===
 
 
===Foodborne Botulism=== <!--T:3-->
 
<!--T:4-->
*Equine Serum Botulism Antitoxin
*Equine Serum Botulism Antitoxin
**only for patients > 1yo
**only for patients > 1yo
*Antitoxin obtained through department of health / CDC. Hotline in LA: (888) 397-3993<ref name="LA DOH">http://www.publichealth.lacounty.gov/acd/Cdrs.htm</ref>
*Antitoxin obtained through CDC or local Department of Health.


===Infant Botulism (<1yo)===
 
===Infant Botulism (<1yo)=== <!--T:5-->
 
<!--T:6-->
*Human-based Botulism IG 100mg/kg IV x 1 dose (BabyBIG)
*Human-based Botulism IG 100mg/kg IV x 1 dose (BabyBIG)
**infusion divided into 25mg/kg/hr IV x 15 min FOLLOWED by 50mg/kg/hr if no allergic reactions
**infusion divided into 25mg/kg/hr IV x 15 min followed by 50mg/kg/hr if no allergic reactions
**Stop infusion after total of 100mg/kg infused
**Stop infusion after total of 100mg/kg infused
*To report suspected cases and obtain BabyBIG: California DHS Infant Botulism Treatment and Prevention Program: (510) 231-7600<ref>http://www.infantbotulism.org/</ref>
*BabyBIG obtained through CDC or local Department of Health


===Inhalational Botulism===
 
===Inhalational Botulism=== <!--T:7-->
 
<!--T:8-->
*Equine Serum Botulism Antitoxin
*Equine Serum Botulism Antitoxin
**only for patients > 1yo
**only for patients > 1yo
*Antitoxin obtained through dept of health / CDC. Hotline in LA: (888) 397-3993<ref name="LA DOH"/>
*Antitoxin obtained through CDC or local Department of Health
 
 
===Wound Botulism=== <!--T:9-->


===Wound Botulism===
<!--T:10-->
*Individualize therapy with ID consultant
*Individualize therapy with ID consultant
*Broad antibiotic coverage same as for [[Necrotizing fasciitis]] while awaiting wound cultures
*Broad antibiotic coverage same as for [[Special:MyLanguage/Necrotizing fasciitis|Necrotizing fasciitis]] while awaiting wound cultures
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Latest revision as of 04:27, 26 January 2026

Other languages:

Supportive Care

  • Early ventilatory support
    • Consider intubation when vital capacity <30% predicted or <12cc/kg
  • Wound Managment
    • Early wound debreedment with surgical consult.
    • Also exclude Necrotizing fasciitis and coverage with same broad antibiotic coverage


Foodborne Botulism

  • Equine Serum Botulism Antitoxin
    • only for patients > 1yo
  • Antitoxin obtained through CDC or local Department of Health.


Infant Botulism (<1yo)

  • Human-based Botulism IG 100mg/kg IV x 1 dose (BabyBIG)
    • infusion divided into 25mg/kg/hr IV x 15 min followed by 50mg/kg/hr if no allergic reactions
    • Stop infusion after total of 100mg/kg infused
  • BabyBIG obtained through CDC or local Department of Health


Inhalational Botulism

  • Equine Serum Botulism Antitoxin
    • only for patients > 1yo
  • Antitoxin obtained through CDC or local Department of Health


Wound Botulism

  • Individualize therapy with ID consultant
  • Broad antibiotic coverage same as for Necrotizing fasciitis while awaiting wound cultures