Template:Botulism treatment
Contents
Supportive Care
- Early ventilatory support
- Consider intubation when vital capacity <30% predicted or <12cc/kg
- Wound Managment
- Early wound debreedment with surgical consult.
- Also exclude Necrotizing fasciitis and coverage with same broad antibiotic coverage
Foodborne Botulism
- Equine Serum Botulism Antitoxin
- only for patients > 1yo
- Antitoxin obtained through CDC or local Department of Health.
Infant Botulism (<1yo)
- Human-based Botulism IG 100mg/kg IV x 1 dose (BabyBIG)
- infusion divided into 25mg/kg/hr IV x 15 min followed by 50mg/kg/hr if no allergic reactions
- Stop infusion after total of 100mg/kg infused
- BabyBIG obtained through CDC or local Department of Health
Inhalational Botulism
- Equine Serum Botulism Antitoxin
- only for patients > 1yo
- Antitoxin obtained through CDC or local Department of Health
Wound Botulism
- Individualize therapy with ID consultant
- Broad antibiotic coverage same as for Necrotizing fasciitis while awaiting wound cultures