Sympathetic ophthalmia: Difference between revisions
(Created page with "==Symathetic Ophthalmia== *Uveitis of both eyes, following trauma to one eye **Due to autoimmune inflammatory response after introduction of immune system to ocular antigens d...") |
ClaireLewis (talk | contribs) No edit summary |
||
| (8 intermediate revisions by 4 users not shown) | |||
| Line 1: | Line 1: | ||
== | ==Background== | ||
*Uveitis of both eyes, following trauma to one eye | *[[Uveitis]] of both eyes, following trauma to one eye | ||
**Due to autoimmune inflammatory response after introduction of immune system to ocular antigens during trauma | **Due to autoimmune inflammatory response after introduction of immune system to ocular antigens during trauma | ||
**Can develop within days to years of initial trauma | **Can develop within days to years of initial trauma | ||
**Affects 0.03 per 100,000 persons per year | |||
*Prevention | |||
**Because it is so rare, enucleation often not done immediately, if chance of regaining function | |||
==Clinical Features== | |||
*Symptoms | *Symptoms | ||
**Floaters | **[[Floaters]] | ||
**Loss of accommodation | **Loss of accommodation | ||
** | **[[Eye pain]], photophobia | ||
==Differential Diagnosis== | |||
{{Acute onset flashers and floaters DDX}} | |||
==Evaluation== | |||
===Work-up=== | |||
===Evaluation=== | |||
==Management== | |||
*Immunosuppressive therapy | |||
*Mild: [[topical steroids]] and pupillary dilators | |||
*Severe: Systemic [[steroids]], chlorambucil, [[cyclophosphamide]] | |||
*Enucleation can reduce symptoms even after the condition has developed | |||
==Disposition== | |||
==See Also== | |||
==External Links== | |||
==References== | |||
<references/> | |||
*Rosen's Emergency Medicine | |||
*Sympathetic Ophthalmia: https://en.wikipedia.org/wiki/Sympathetic_ophthalmia. Updated on 17 September 2014. | |||
[[Category:Ophthalmology]] | |||
Latest revision as of 23:20, 13 November 2016
Background
- Uveitis of both eyes, following trauma to one eye
- Due to autoimmune inflammatory response after introduction of immune system to ocular antigens during trauma
- Can develop within days to years of initial trauma
- Affects 0.03 per 100,000 persons per year
- Prevention
- Because it is so rare, enucleation often not done immediately, if chance of regaining function
Clinical Features
Differential Diagnosis
Acute onset flashers and floaters
- Ocular causes
- Floaters and/or flashes
- Posterior vitreous detachment
- Retinal tear or retinal detachment
- Posterior uveitis
- Predominantly floaters
- Vitreous hemorrhage secondary to proliferative retinopathy
- Sympathetic ophthalmia
- Predominantly flashes
- Oculodigital stimulation
- Rapid eye movements
- Neovascular age-related macular degeneration
- Floaters and/or flashes
- Non-ocular causes
- Intraocular foreign body
- Migraine aura (classic)
- Migraine aura (acephalgicmigraine)
- Occipital lobe disorders
- Postural hypotension
Evaluation
Work-up
Evaluation
Management
- Immunosuppressive therapy
- Mild: topical steroids and pupillary dilators
- Severe: Systemic steroids, chlorambucil, cyclophosphamide
- Enucleation can reduce symptoms even after the condition has developed
Disposition
See Also
External Links
References
- Rosen's Emergency Medicine
- Sympathetic Ophthalmia: https://en.wikipedia.org/wiki/Sympathetic_ophthalmia. Updated on 17 September 2014.