Cephalosporins: Difference between revisions
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==1st Generation== | ==1st Generation== | ||
*Skin and soft tissue infections (why is agent of choice before | *Skin and soft tissue infections (why is agent of choice before generalized symptoms) | ||
*[[ | *[[EBQ:Cephalosporin Cross-reactivity|Cross-reactivity of PCN]] allergy <10% | ||
==2nd Generation== | ==2nd Generation== | ||
| Line 9: | Line 9: | ||
==3rd Generation== | ==3rd Generation== | ||
*Drug of choice for serious infections due to: | *Drug of choice for serious infections due to: | ||
**Klebsiella | **[[Klebsiella]] | ||
**Enterobacter | **[[Enterobacter]] | ||
**Proteus | **Proteus | ||
**Haemophilus | **[[Haemophilus]] | ||
*[[Gonorrhea]] | *[[Gonorrhea]] | ||
*[[Lyme Disease]] | *[[Lyme Disease]] | ||
*[[Meningitis]] (+ [[vanc]] and [[ampicillin]]) | *[[Meningitis]] (+ [[vanc]] and [[ampicillin]]) | ||
*Pseudomonas meningitis (+ AG) | *[[Pseudomonas]] meningitis (+ AG) | ||
==4th Generation== | ==4th Generation== | ||
*Resistant, nosocomial infections | *Resistant, nosocomial infections | ||
{{ | {{Clinically Utilized Antibiotics}} | ||
==See Also== | ==See Also== | ||
Latest revision as of 01:29, 21 February 2021
1st Generation
- Skin and soft tissue infections (why is agent of choice before generalized symptoms)
- Cross-reactivity of PCN allergy <10%
2nd Generation
- Intestinal anaerobes (why is agent of choice for colorectal sx)
- Largely displaced by 3rd gen agents
3rd Generation
- Drug of choice for serious infections due to:
- Klebsiella
- Enterobacter
- Proteus
- Haemophilus
- Gonorrhea
- Lyme Disease
- Meningitis (+ vanc and ampicillin)
- Pseudomonas meningitis (+ AG)
4th Generation
- Resistant, nosocomial infections
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See Also
References
Goodman & Gilman's Pharmacology