Triamcinolone acetonide: Difference between revisions
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==Administration== | ==Administration== | ||
*Type: [[Topical | *Type: [[Topical steroids]] | ||
*Dosage Forms: 0.5% | *Dosage Forms: Ointment/Cream: 0.025%, 0.5% . Nasal spray: 55 mcg/spray | ||
*Routes of Administration: Topical | *Routes of Administration: Topical, intranasal | ||
*Common Trade Names: Kenalog, Aristocort cream | *Common Trade Names: Kenalog, Aristocort cream, Nasocort | ||
==Adult Dosing== | ==Adult Dosing== | ||
*Skin disorders | |||
**Apply to affected areas 2-4 times per day | |||
*[[Allergic rhinitis]] | |||
**2 sprays in each nostril 1-2 times per day | |||
==Pediatric Dosing== | ==Pediatric Dosing== | ||
*Topical: apply to affected area 2-4 times per day | |||
*Intranasal: | |||
**6-12yo: 1 spray in each nostril 1-2 times per day | |||
**2-5yo: 1 spray in each nostril once daily | |||
==Special Populations== | ==Special Populations== | ||
*[[Drug Ratings in Pregnancy|Pregnancy Rating]]: | *[[Drug Ratings in Pregnancy|Pregnancy Rating]]: C | ||
*[[Lactation risk categories|Lactation risk]]: | *[[Lactation risk categories|Lactation risk]]: Infant risk cannot be ruled out | ||
===Renal Dosing=== | ===Renal Dosing=== | ||
*Adult: | *Adult: | ||
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==Contraindications== | ==Contraindications== | ||
*Allergy to class/drug | *Allergy to class/drug | ||
*Avoid applying to groin or open skin | |||
==Adverse Reactions== | ==Adverse Reactions== | ||
===Serious=== | ===Serious=== | ||
*Secondary hypocortisolism (Very rare with topicals, only with prolonged use of high-potency ointment over large areas) | |||
===Common=== | ===Common=== | ||
*No truly "common" adverse reaction for topical/intranasal forms, but may | |||
==Pharmacology== | ==Pharmacology== | ||
*Absorption: Percutaneous absorption: bioavailability 1-7% for areas excluding groin. Intranasal bioavailability minimal | |||
*Half-life: | *Half-life: | ||
*Metabolism: | *Metabolism: | ||
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==Mechanism of Action== | ==Mechanism of Action== | ||
*Adrenal glucocorticoid | |||
==Comments== | ==Comments== | ||
==See Also== | ==See Also== | ||
*[[Topical steroids]] | |||
==References== | ==References== | ||
<references/> | <references/> | ||
[[Category:Pharmacology]] | [[Category:Pharmacology]] | ||
[[Category:Dermatology]] | |||
Latest revision as of 23:07, 23 September 2019
Administration
- Type: Topical steroids
- Dosage Forms: Ointment/Cream: 0.025%, 0.5% . Nasal spray: 55 mcg/spray
- Routes of Administration: Topical, intranasal
- Common Trade Names: Kenalog, Aristocort cream, Nasocort
Adult Dosing
- Skin disorders
- Apply to affected areas 2-4 times per day
- Allergic rhinitis
- 2 sprays in each nostril 1-2 times per day
Pediatric Dosing
- Topical: apply to affected area 2-4 times per day
- Intranasal:
- 6-12yo: 1 spray in each nostril 1-2 times per day
- 2-5yo: 1 spray in each nostril once daily
Special Populations
- Pregnancy Rating: C
- Lactation risk: Infant risk cannot be ruled out
Renal Dosing
- Adult:
- Pediatric:
Hepatic Dosing
- Adult:
- Pediatric:
Contraindications
- Allergy to class/drug
- Avoid applying to groin or open skin
Adverse Reactions
Serious
- Secondary hypocortisolism (Very rare with topicals, only with prolonged use of high-potency ointment over large areas)
Common
- No truly "common" adverse reaction for topical/intranasal forms, but may
Pharmacology
- Absorption: Percutaneous absorption: bioavailability 1-7% for areas excluding groin. Intranasal bioavailability minimal
- Half-life:
- Metabolism:
- Excretion:
Mechanism of Action
- Adrenal glucocorticoid