Triamcinolone acetonide

Administration

  • Type: Topical steroids
  • Dosage Forms: Ointment/Cream: 0.025%, 0.5% . Nasal spray: 55 mcg/spray
  • Routes of Administration: Topical, intranasal
  • Common Trade Names: Kenalog, Aristocort cream, Nasocort

Adult Dosing

  • Skin disorders
    • Apply to affected areas 2-4 times per day
  • Allergic rhinitis
    • 2 sprays in each nostril 1-2 times per day

Pediatric Dosing

  • Topical: apply to affected area 2-4 times per day
  • Intranasal:
    • 6-12yo: 1 spray in each nostril 1-2 times per day
    • 2-5yo: 1 spray in each nostril once daily

Special Populations

Renal Dosing

  • Adult:
  • Pediatric:

Hepatic Dosing

  • Adult:
  • Pediatric:

Contraindications

  • Allergy to class/drug
  • Avoid applying to groin or open skin

Adverse Reactions

Serious

  • Secondary hypocortisolism (Very rare with topicals, only with prolonged use of high-potency ointment over large areas)

Common

  • No truly "common" adverse reaction for topical/intranasal forms, but may

Pharmacology

  • Absorption: Percutaneous absorption: bioavailability 1-7% for areas excluding groin. Intranasal bioavailability minimal
  • Half-life:
  • Metabolism:
  • Excretion:

Mechanism of Action

  • Adrenal glucocorticoid

Comments

See Also

References