Carbon disulfide toxicity: Difference between revisions
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*Also a metabolite of drug Disulfiram | *Also a metabolite of drug Disulfiram | ||
==Mechanism of Toxicity== | ===Mechanism of Toxicity=== | ||
*Disruption of enzymes and metabolic pathways including in the CNS | *Disruption of enzymes and metabolic pathways including in the CNS | ||
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*Skin irritation | *Skin irritation | ||
*CNS depression | *CNS depression | ||
==Differential Diagnosis== | |||
==Diagnosis== | ==Diagnosis== | ||
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==Treatment== | ==Treatment== | ||
*Decontaminate | *Decontaminate | ||
*Consider activated charcoal for oral ingestions | *Consider [[activated charcoal]] for oral ingestions | ||
*No specific antidotes available | *No specific antidotes available | ||
==Disposition== | |||
==See Also== | ==See Also== | ||
==References== | ==References== | ||
Olson, K. Poisoning and Drug Overdose, 1999. | *Olson, K. Poisoning and Drug Overdose, 1999. | ||
Revision as of 05:02, 10 April 2017
Background
- Organic Solvent
- Precursor in rubber industry
- Also a metabolite of drug Disulfiram
Mechanism of Toxicity
- Disruption of enzymes and metabolic pathways including in the CNS
Clinical Features
- Eye irritation
- Skin irritation
- CNS depression
Differential Diagnosis
Diagnosis
- Based on clinical history and presenting signs and symptoms
Treatment
- Decontaminate
- Consider activated charcoal for oral ingestions
- No specific antidotes available
Disposition
See Also
References
- Olson, K. Poisoning and Drug Overdose, 1999.