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==General==
==General==
*Type: Amino-[[Penicillin]]
*Type: Amino-[[Penicillin]]
*Dosage Forms:
*Dosage Forms: 250, 500, 875; 125, 200, 250, 400/5 mL
*Common Trade Names:
*Common Trade Names: Amoxil; Moxatag


==Adult Dosing==
==Adult Dosing==
===General===
*500-875 mg PO q12
===[[Strep Pharyngitis]]===
*1000 mg PO q24h x 10 days
===[[Otitis Media]]===
*1000 mg PO q8h x 10 days
===[[Sinusitis]]===
*1000 mg PO q8h x 10 days
===[[Dental Abscess]]===
*1000 mg PO x 1, then 500 mg PO q8h x 3 days
*If [[I&D]]
===[[Chlamydial]] [[Cervicitis]]/[[Urethritis]]===
*500 mg PO q8h x 7 days
*For pregnant patients
===[[Lyme Disease]]===
*500mg PO q8h x 14-21 days
===[[Salmonella]]===
''Not 1st line treatment''
*Acute
**Immunocompetent
***500mg PO q8h x 3-7 days
**Immunocompromised
***1000mg PO q8h x 3-14 days
*Chronic carrier
**1000mg PO q8h x 3 months
===Typhoid Fever===
''Not 1st line treatment''
*50-100 mg/kg/day PO divided q6-8h x 14 days
*First Dose: 12.5mg-33.3 mg/kg PO x 1


==Pediatric Dosing==
==Pediatric Dosing==
===General===
*'''<3mo:''' 20-30 mg/kg/day PO divided q12h
**First Dose: 10-15 mg/kg PO x 1
**Max: 30 mg/kg/day
*'''>3mo:''' 25-45 mg/kg/day PO divided q12h
**First Dose: 12.5-22.5 mg/kg PO x 1
**Max: 875 mg/dose
===[[Otitis Media]]===
*'''<2 months'''
**30 mg/kg/day PO divided q12h x 10 days
**First Dose: 15 mg/kg PO x 1
*'''2 months - 5 years'''
**80-90 mg/kg/day PO divided q12h x 10 days
**First Dose: 40-45 mg/kg PO x 1
**Max: 1000 mg/dose
*'''6-12 years'''
**80-90 mg/kg/day PO divided q12h x 5-10 days
**First Dose: 40-45 mg/kg/day PO x 1
**Max: 1000 mg/dose
===Community Acquired [[Pneumonia]]===
*90 mg/kg/day PO divided q12h x 5-10 days
*First Dose: 45 mg/kg PO x 1
**Max
***3 months - 4 years: 500 mg/dose
***>5 years: 4000 mg/day
===[[Strep Pharyngitis]]===
*50 mg/kg Po q24h x 10 days
*Max: 1000 mg/day
===[[Sinusitis]]===
*90 mg/kg/day PO divided q8-12h x 10 days
*Max: 1000 mg/dose
===H. pylori===
*50 mg/kg/day PO divided BID x 7-14 days
*Max: 2000 mg/day
===Early [[[Lyme Disease]]===
*50 mg/kg/day PO divided q8h x 14-21 days
*First Dose: 16.6 mg/kg PO x1
*Max: 500 mg/dose
===Salmonella (>3mo)===
*50-100 mg/kg/day PO divided q8-12h
**Acute: x 3-7 days
**Acute Immunocompromised: 10-14 days
**Chronic: 3 months
===[[Typhoid Fever]] (>3mo)===
''Not 1st line treatment''
*50-100 mg/kg/day PO divided q6-8h x 14 days


==Special Populations==
==Special Populations==

Revision as of 05:17, 29 March 2014

General

  • Type: Amino-Penicillin
  • Dosage Forms: 250, 500, 875; 125, 200, 250, 400/5 mL
  • Common Trade Names: Amoxil; Moxatag

Adult Dosing

General

  • 500-875 mg PO q12

Strep Pharyngitis

  • 1000 mg PO q24h x 10 days

Otitis Media

  • 1000 mg PO q8h x 10 days

Sinusitis

  • 1000 mg PO q8h x 10 days

Dental Abscess

  • 1000 mg PO x 1, then 500 mg PO q8h x 3 days
  • If I&D

Chlamydial Cervicitis/Urethritis

  • 500 mg PO q8h x 7 days
  • For pregnant patients

Lyme Disease

  • 500mg PO q8h x 14-21 days

Salmonella

Not 1st line treatment

  • Acute
    • Immunocompetent
      • 500mg PO q8h x 3-7 days
    • Immunocompromised
      • 1000mg PO q8h x 3-14 days
  • Chronic carrier
    • 1000mg PO q8h x 3 months

Typhoid Fever

Not 1st line treatment

  • 50-100 mg/kg/day PO divided q6-8h x 14 days
  • First Dose: 12.5mg-33.3 mg/kg PO x 1

Pediatric Dosing

General

  • <3mo: 20-30 mg/kg/day PO divided q12h
    • First Dose: 10-15 mg/kg PO x 1
    • Max: 30 mg/kg/day
  • >3mo: 25-45 mg/kg/day PO divided q12h
    • First Dose: 12.5-22.5 mg/kg PO x 1
    • Max: 875 mg/dose

Otitis Media

  • <2 months
    • 30 mg/kg/day PO divided q12h x 10 days
    • First Dose: 15 mg/kg PO x 1
  • 2 months - 5 years
    • 80-90 mg/kg/day PO divided q12h x 10 days
    • First Dose: 40-45 mg/kg PO x 1
    • Max: 1000 mg/dose
  • 6-12 years
    • 80-90 mg/kg/day PO divided q12h x 5-10 days
    • First Dose: 40-45 mg/kg/day PO x 1
    • Max: 1000 mg/dose

Community Acquired Pneumonia

  • 90 mg/kg/day PO divided q12h x 5-10 days
  • First Dose: 45 mg/kg PO x 1
    • Max
      • 3 months - 4 years: 500 mg/dose
      • >5 years: 4000 mg/day

Strep Pharyngitis

  • 50 mg/kg Po q24h x 10 days
  • Max: 1000 mg/day

Sinusitis

  • 90 mg/kg/day PO divided q8-12h x 10 days
  • Max: 1000 mg/dose

H. pylori

  • 50 mg/kg/day PO divided BID x 7-14 days
  • Max: 2000 mg/day

Early [[[Lyme Disease]]

  • 50 mg/kg/day PO divided q8h x 14-21 days
  • First Dose: 16.6 mg/kg PO x1
  • Max: 500 mg/dose

Salmonella (>3mo)

  • 50-100 mg/kg/day PO divided q8-12h
    • Acute: x 3-7 days
    • Acute Immunocompromised: 10-14 days
    • Chronic: 3 months

Typhoid Fever (>3mo)

Not 1st line treatment

  • 50-100 mg/kg/day PO divided q6-8h x 14 days

Special Populations

  • Pregnancy Rating:
  • Lactation:
  • Renal Dosing
    • Adult
    • Pediatric
  • Hepatic Dosing
    • Adult
    • Pediatric

Contraindications

  • Allergy to class/drug

Adverse Reactions

Serious

Common

Pharmacology

  • Half-life:
  • Metabolism:
  • Excretion:
  • Mechanism of Action:

See Also

Source

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