Methicillin: Difference between revisions
Line 46: Line 46:
| ||Strep. anginosus gp||'''S'''
| ||Strep. anginosus gp||'''S'''
|-
|-
| ||[[Enterococcus faecalis]]||'''S'''
| ||[[Enterococcus faecalis]]||R
|-
|-
| ||[[Enterococcus faecium]]||I
| ||[[Enterococcus faecium]]||R
|-
|-
| ||[[MSSA]]||R
| ||[[MSSA]]||'''S'''
|-
|-
| ||[[MRSA]]||R
| ||[[MRSA]]||R
Line 56: Line 56:
| ||[[CA-MRSA]]||R
| ||[[CA-MRSA]]||R
|-
|-
| ||[[Staph. Epidermidis]]||R
| ||[[Staph. Epidermidis]]||'''S'''
|-
|-
| ||[[C. jeikeium]]||R
| ||[[C. jeikeium]]||R
Line 122: Line 122:
| ||[[Legionella sp.]]||R
| ||[[Legionella sp.]]||R
|-
|-
| ||[[Pasteurella multocida]]||'''S'''
| ||[[Pasteurella multocida]]||R
|-
|-
| ||[[Haemophilus ducreyi]]||X1
| ||[[Haemophilus ducreyi]]||X1
Line 136: Line 136:
| ||[[Mycobacterium avium]]||X1
| ||[[Mycobacterium avium]]||X1
|-
|-
| Anaerobes||[[Actinomyces]]||I
| Anaerobes||[[Actinomyces]]||R
|-
|-
| ||[[Bacteroides fragilis]]||I
| ||[[Bacteroides fragilis]]||R
|-
|-
| ||[[Prevotella melaninogenica]]||R
| ||[[Prevotella melaninogenica]]||R
Line 144: Line 144:
| ||[[Clostridium difficile]]||X1
| ||[[Clostridium difficile]]||X1
|-
|-
| ||[[Clostridium (not difficile)]]||'''S'''
| ||[[Clostridium (not difficile)]]||X1
|-
|-
| ||[[Fusobacterium necrophorum]]||I
| ||[[Fusobacterium necrophorum]]||X1
|-
|-
| ||[[Peptostreptococcus sp.]]||'''S'''
| ||[[Peptostreptococcus sp.]]||'''S'''

Revision as of 03:15, 24 June 2014

General

  • Type:
  • Dosage Forms:
  • Common Trade Names:

Adult Dosing

Pediatric Dosing

Special Populations

  • Pregnancy Rating:
  • Lactation:
  • Renal Dosing
    • Adult
    • Pediatric
  • Hepatic Dosing
    • Adult
    • Pediatric

Contraindications

  • Allergy to class/drug

Adverse Reactions

Serious

Common

Pharmacology

  • Half-life:
  • Metabolism:
  • Excretion:
  • Mechanism of Action:

Antibiotic Sensitivities[1]

Group Organism Sensitivity
Gram Positive Strep. Group A, B, C, G S
Strep. Pneumoniae S
Viridans strep I
Strep. anginosus gp S
Enterococcus faecalis R
Enterococcus faecium R
MSSA S
MRSA R
CA-MRSA R
Staph. Epidermidis S
C. jeikeium R
L. monocytogenes R
Gram Negatives N. gonorrhoeae R
N. meningitidis R
Moraxella catarrhalis R
H. influenzae R
E. coli R
Klebsiella sp R
E. coli/Klebsiella ESBL+ R
E coli/Klebsiella KPC+ R
Enterobacter sp, AmpC neg R
Enterobacter sp, AmpC pos R
Serratia sp R
Serratia marcescens X1
Salmonella sp R
Shigella sp R
Proteus mirabilis R
Proteus vulgaris R
Providencia sp. R
Morganella sp. R
Citrobacter freundii R
Citrobacter diversus R
Citrobacter sp. R
Aeromonas sp R
Acinetobacter sp. R
Pseudomonas aeruginosa R
Burkholderia cepacia R
Stenotrophomonas maltophilia R
Yersinia enterocolitica R
Francisella tularensis X1
Brucella sp. X1
Legionella sp. R
Pasteurella multocida R
Haemophilus ducreyi X1
Vibrio vulnificus X1
Misc Chlamydophila sp R
Mycoplasm pneumoniae R
Rickettsia sp X1
Mycobacterium avium X1
Anaerobes Actinomyces R
Bacteroides fragilis R
Prevotella melaninogenica R
Clostridium difficile X1
Clostridium (not difficile) X1
Fusobacterium necrophorum X1
Peptostreptococcus sp. S

Key

  • S susceptible/sensitive (usually)
  • I intermediate (variably susceptible/resistant)
  • R resistant (or not effective clinically)
  • S+ synergistic with cell wall antibiotics
  • U sensitive for UTI only (non systemic infection)
  • X1 no data
  • X2 active in vitro, but not used clinically
  • X3 active in vitro, but not clinically effective for Group A strep pharyngitis or infections due to E. faecalis
  • X4 active in vitro, but not clinically effective for strep pneumonia

See Also

Source

  1. ↑ Sanford Guide to Antimicrobial Therapy 2014
Retrieved from "https://www.wikem.org/w/index.php?title=Methicillin&oldid=21974"