Sandbox

System	Minor or moderate overdose	Severe overdose
Cardiovascular		Disseminated intravascular coagulation Intracranial hemorrhage Severe hypertension or hypotension Hypotensive bleeding
Central nervous system	Hyperreflexia Agitation Confusion Paranoia Stimulant psychosis	Cognitive deficit Coma Convulsions Hallucinations Loss of consciousness Serotonin syndrome
Musculoskeletal		Hypertonia Rhabdomyolysis
Respiratory		Acute respiratory distress syndrome
Urinary		Acute kidney injury
Other		Cerebral edema Hepatitis Hyperpyrexia Hyponatremia (SIAD)