Sympathetic ophthalmia: Difference between revisions
(Created page with "==Symathetic Ophthalmia== *Uveitis of both eyes, following trauma to one eye **Due to autoimmune inflammatory response after introduction of immune system to ocular antigens d...") |
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**Due to autoimmune inflammatory response after introduction of immune system to ocular antigens during trauma | **Due to autoimmune inflammatory response after introduction of immune system to ocular antigens during trauma | ||
**Can develop within days to years of initial trauma | **Can develop within days to years of initial trauma | ||
**Affects 0.03 per 100,000 persons per year | |||
*Symptoms | *Symptoms | ||
**Floaters | **Floaters | ||
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**Mild: local corticosteroids and pupillary dilators | **Mild: local corticosteroids and pupillary dilators | ||
**Severe: Systemic steroids, chlorambucil, cyclophosphamide | **Severe: Systemic steroids, chlorambucil, cyclophosphamide | ||
**Enucleation can reduce symptoms even after the condition has developed | |||
Revision as of 22:40, 31 August 2015
Symathetic Ophthalmia
- Uveitis of both eyes, following trauma to one eye
- Due to autoimmune inflammatory response after introduction of immune system to ocular antigens during trauma
- Can develop within days to years of initial trauma
- Affects 0.03 per 100,000 persons per year
- Symptoms
- Floaters
- Loss of accommodation
- Pain, photophobia
- Prevention
- Because it is so rare, enucleation often not done immediately, if chance of regaining function
- Treatment
- Immunosuppressive therapy
- Mild: local corticosteroids and pupillary dilators
- Severe: Systemic steroids, chlorambucil, cyclophosphamide
- Enucleation can reduce symptoms even after the condition has developed