Sympathetic ophthalmia: Difference between revisions
(references) |
|||
| Line 1: | Line 1: | ||
== | ==Sympathetic Ophthalmia== | ||
*Uveitis of both eyes, following trauma to one eye | *Uveitis of both eyes, following trauma to one eye | ||
**Due to autoimmune inflammatory response after introduction of immune system to ocular antigens during trauma | **Due to autoimmune inflammatory response after introduction of immune system to ocular antigens during trauma | ||
| Line 15: | Line 15: | ||
**Severe: Systemic steroids, chlorambucil, cyclophosphamide | **Severe: Systemic steroids, chlorambucil, cyclophosphamide | ||
**Enucleation can reduce symptoms even after the condition has developed | **Enucleation can reduce symptoms even after the condition has developed | ||
==References== | |||
*Rosen's Emergency Medicine | |||
*Sympathetic Ophthalmia: https://en.wikipedia.org/wiki/Sympathetic_ophthalmia. Updated on 17 September 2014. | |||
Revision as of 22:43, 31 August 2015
Sympathetic Ophthalmia
- Uveitis of both eyes, following trauma to one eye
- Due to autoimmune inflammatory response after introduction of immune system to ocular antigens during trauma
- Can develop within days to years of initial trauma
- Affects 0.03 per 100,000 persons per year
- Symptoms
- Floaters
- Loss of accommodation
- Pain, photophobia
- Prevention
- Because it is so rare, enucleation often not done immediately, if chance of regaining function
- Treatment
- Immunosuppressive therapy
- Mild: local corticosteroids and pupillary dilators
- Severe: Systemic steroids, chlorambucil, cyclophosphamide
- Enucleation can reduce symptoms even after the condition has developed
References
- Rosen's Emergency Medicine
- Sympathetic Ophthalmia: https://en.wikipedia.org/wiki/Sympathetic_ophthalmia. Updated on 17 September 2014.