Sympathetic ophthalmia: Difference between revisions

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Revision as of 03:52, 1 September 2015

Sympathetic Ophthalmia

  • Uveitis of both eyes, following trauma to one eye
    • Due to autoimmune inflammatory response after introduction of immune system to ocular antigens during trauma
    • Can develop within days to years of initial trauma
    • Affects 0.03 per 100,000 persons per year
  • Symptoms
    • Floaters
    • Loss of accommodation
    • Pain, photophobia
  • Prevention
    • Because it is so rare, enucleation often not done immediately, if chance of regaining function
  • Treatment
    • Immunosuppressive therapy
    • Mild: local corticosteroids and pupillary dilators
    • Severe: Systemic steroids, chlorambucil, cyclophosphamide
    • Enucleation can reduce symptoms even after the condition has developed

References