Esophageal candidiasis: Difference between revisions
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==Background== | ==Background== | ||
* Most commonly seen in [[HIV]] patients with CD4 count < 100 (AIDS-defining illness) or chronic inhaled glucocorticoid use | *Most commonly seen in [[HIV]] patients with CD4 count < 100 (AIDS-defining illness) or chronic inhaled glucocorticoid use | ||
==Clinical Features<ref name=candida>Kauffmann CA. Overview of Candida Infections. UptoDate. 2016.</ref>== | ==Clinical Features<ref name=candida>Kauffmann CA. Overview of Candida Infections. UptoDate. 2016.</ref>== | ||
* odynophagia | *odynophagia | ||
* dysphagia | *dysphagia | ||
* retrosternal pain | *retrosternal pain | ||
* [[nausea/vomiting]] | *[[nausea/vomiting]] | ||
==Differential Diagnosis== | ==Differential Diagnosis== | ||
===[[Esophagitis]]=== | ===[[Esophagitis]]=== | ||
*Esophageal candidiasis | *Esophageal candidiasis | ||
* Cytomegalovirus esophagitis | *Cytomegalovirus esophagitis | ||
* Herpes Simplex esophagitis | *Herpes Simplex esophagitis | ||
* Eosinophilic esophagitis | *Eosinophilic esophagitis | ||
* Medication-induced esophagitis | *Medication-induced esophagitis | ||
==Evaluation== | ==Evaluation== | ||
| Line 21: | Line 21: | ||
==Management== | ==Management== | ||
* [[Fluconazole]] 400mg PO loading dose, followed by 200mg PO Qdaily x 2 weeks | *[[Fluconazole]] 400mg PO loading dose, followed by 200mg PO Qdaily x 2 weeks | ||
*[[Itraconazole]] 200mg PO Qdaily for 2 weeks | *[[Itraconazole]] 200mg PO Qdaily for 2 weeks | ||
** has more nausea side-effects and drug interactions compared to fluconazole | **has more nausea side-effects and drug interactions compared to fluconazole | ||
==Disposition== | ==Disposition== | ||
Revision as of 15:50, 27 October 2016
Background
- Most commonly seen in HIV patients with CD4 count < 100 (AIDS-defining illness) or chronic inhaled glucocorticoid use
Clinical Features[1]
- odynophagia
- dysphagia
- retrosternal pain
- nausea/vomiting
Differential Diagnosis
Esophagitis
- Esophageal candidiasis
- Cytomegalovirus esophagitis
- Herpes Simplex esophagitis
- Eosinophilic esophagitis
- Medication-induced esophagitis
Evaluation
- Thick, white, linear esophageal plaques on endoscopy
Management
- Fluconazole 400mg PO loading dose, followed by 200mg PO Qdaily x 2 weeks
- Itraconazole 200mg PO Qdaily for 2 weeks
- has more nausea side-effects and drug interactions compared to fluconazole
Disposition
See Also
External Links
References
- ↑ Kauffmann CA. Overview of Candida Infections. UptoDate. 2016.