Digoxin: Difference between revisions
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== Adult Dosing == | == Adult Dosing == | ||
*Loading dose = 0.25 mg IV q2hr until effect (max total = 1.5 mg) | *Loading dose = 0.25 mg IV q2hr until effect (max total = 1.5 mg) | ||
*in afib with HF = 0.5 mg iV, 0.25 mg in 4 hours, 0.125 in 2 hours | |||
== Contraindications == | == Contraindications == | ||
Revision as of 19:42, 18 April 2013
Adult Dosing
- Loading dose = 0.25 mg IV q2hr until effect (max total = 1.5 mg)
- in afib with HF = 0.5 mg iV, 0.25 mg in 4 hours, 0.125 in 2 hours
Contraindications
- WPW
- Increases conduction velocity in atrial tissue
Indications
- RVR control in a-fib/flutter, PSVT
Mechanism of Action
- Inhibits NaK pump
- Positive inotropy
- Negative chronotropy/dromotropy
- Indirect vagal stimulator
Adverse Drug Reactions
- GI: N/V, diarrhea, abd pain
- CV: Bradycardia, SA/AV block, ventr arrhythmias
Kinetics
- Onset of action = 1.5-4hr (IV)