Metabolic dysfunction-associated steatohepatitis (MASH): Difference between revisions
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==Background== | ==Background== | ||
[[File:Stage of liver damage high.jpg|thumb|Stages of non-alcoholic fatty liver disease, progressing from healthy, to steatosis (fat accumulation), inflammation, fibrosis and cirrhosis.]] | |||
*Fatty liver disease due to causes other than excessive alcohol | *Fatty liver disease due to causes other than excessive alcohol | ||
*Associated with insulin resistance and [[metabolic syndrome]] | *Associated with insulin resistance and [[metabolic syndrome]] | ||
Revision as of 19:51, 7 September 2022
Background
- Fatty liver disease due to causes other than excessive alcohol
- Associated with insulin resistance and metabolic syndrome
Clinical Features
- Often asymptomatic or with mild RUQ discomfort
- Signs of portal hypertension (e.g. ascites) if advanced fibrosis
- Hepatomegaly
Differential Diagnosis
- Cirrhosis
- Hepatitis
- Viral hepatitis
- Autoimmune hepatitis
- Wilson's disease
- Hemochromatosis
- Hepatocellular carcinoma
- CHF (right heart failure]]
Evaluation
Management
- Treat complications of portal hypertension, if present
- Counsel on weight loss, increased coffee consumption
- Vitamin E if known F2 fibrosis
Disposition
- Discharge unless complications