Template:Botulism treatment: Difference between revisions
Ostermayer (talk | contribs) (Created page with "If suspect possible bioterrorism, contact CDC +1-770-488-7100 ===Supportive Care=== *Early ventilatory support **Consider intubation when vital capacity <30% predicted or <12c...") |
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**only for patients > 1yo | **only for patients > 1yo | ||
===Infant Botulism (<1yo)=== | ===Infant Botulism (<1yo)=== | ||
*Human-based Botulism IG 100mg/kg IV x 1 dose | *Human-based Botulism IG 100mg/kg IV x 1 dose (BabyBIG) | ||
**infusion divided into 25mg/kg/hr IV x 15 min FOLLOWED by 50mg/kg/hr if no allergic reactions | **infusion divided into 25mg/kg/hr IV x 15 min FOLLOWED by 50mg/kg/hr if no allergic reactions | ||
**Stop infusion after total of 100mg/kg infused | **Stop infusion after total of 100mg/kg infused | ||
*To report suspected cases and obtain BabyBIG: California DHS Infant Botulism Treatment and Prevention Program: (510) 231-7600 | |||
===Inhalational Botulism=== | ===Inhalational Botulism=== | ||
*Equine Serum Botulism Antitoxin | *Equine Serum Botulism Antitoxin | ||
Revision as of 21:06, 24 May 2015
If suspect possible bioterrorism, contact CDC +1-770-488-7100
Supportive Care
- Early ventilatory support
- Consider intubation when vital capacity <30% predicted or <12cc/kg
- Wound Managment
- Early wound debreedment with surgical consult.
- Also exclude Necrotizing fasciitis and coverage with same broad antibiotic coverage
Foodborne Botulism
- Equine Serum Botulism Antitoxin
- only for patients > 1yo
Infant Botulism (<1yo)
- Human-based Botulism IG 100mg/kg IV x 1 dose (BabyBIG)
- infusion divided into 25mg/kg/hr IV x 15 min FOLLOWED by 50mg/kg/hr if no allergic reactions
- Stop infusion after total of 100mg/kg infused
- To report suspected cases and obtain BabyBIG: California DHS Infant Botulism Treatment and Prevention Program: (510) 231-7600
Inhalational Botulism
- Equine Serum Botulism Antitoxin
- only for patients > 1yo
Wound Botulism
- Individualize therapy with ID consultant
- Broad antibiotic coverage same as for Necrotizing fasciitis while awaiting wound cultures