Template:Botulism treatment: Difference between revisions
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===Supportive Care=== | ===Supportive Care=== | ||
*Early ventilatory support | *Early ventilatory support | ||
**Consider intubation when vital capacity <30% predicted or <12cc/kg | **Consider intubation when vital capacity <30% predicted or <12cc/kg | ||
*Wound Managment | *Wound Managment | ||
**Early wound debreedment with surgical consult. | **Early wound debreedment with surgical consult. | ||
**Also exclude [[Necrotizing fasciitis]] and coverage with same broad antibiotic coverage | **Also exclude [[Special:MyLanguage/Necrotizing fasciitis|Necrotizing fasciitis]] and coverage with same broad antibiotic coverage | ||
===Foodborne Botulism=== | ===Foodborne Botulism=== | ||
*Equine Serum Botulism Antitoxin | *Equine Serum Botulism Antitoxin | ||
**only for patients > 1yo | **only for patients > 1yo | ||
*Antitoxin obtained through CDC or local Department of Health. | *Antitoxin obtained through CDC or local Department of Health. | ||
===Infant Botulism (<1yo)=== | ===Infant Botulism (<1yo)=== | ||
*Human-based Botulism IG 100mg/kg IV x 1 dose (BabyBIG) | *Human-based Botulism IG 100mg/kg IV x 1 dose (BabyBIG) | ||
**infusion divided into 25mg/kg/hr IV x 15 min followed by 50mg/kg/hr if no allergic reactions | **infusion divided into 25mg/kg/hr IV x 15 min followed by 50mg/kg/hr if no allergic reactions | ||
**Stop infusion after total of 100mg/kg infused | **Stop infusion after total of 100mg/kg infused | ||
*BabyBIG obtained through CDC or local Department of Health | *BabyBIG obtained through CDC or local Department of Health | ||
===Inhalational Botulism=== | ===Inhalational Botulism=== | ||
*Equine Serum Botulism Antitoxin | *Equine Serum Botulism Antitoxin | ||
**only for patients > 1yo | **only for patients > 1yo | ||
*Antitoxin obtained through CDC or local Department of Health | *Antitoxin obtained through CDC or local Department of Health | ||
===Wound Botulism=== | ===Wound Botulism=== | ||
*Individualize therapy with ID consultant | *Individualize therapy with ID consultant | ||
*Broad antibiotic coverage same as for [[Necrotizing fasciitis]] while awaiting wound cultures | *Broad antibiotic coverage same as for [[Special:MyLanguage/Necrotizing fasciitis|Necrotizing fasciitis]] while awaiting wound cultures | ||
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Revision as of 04:26, 26 January 2026
Supportive Care
- Early ventilatory support
- Consider intubation when vital capacity <30% predicted or <12cc/kg
- Wound Managment
- Early wound debreedment with surgical consult.
- Also exclude Necrotizing fasciitis and coverage with same broad antibiotic coverage
Foodborne Botulism
- Equine Serum Botulism Antitoxin
- only for patients > 1yo
- Antitoxin obtained through CDC or local Department of Health.
Infant Botulism (<1yo)
- Human-based Botulism IG 100mg/kg IV x 1 dose (BabyBIG)
- infusion divided into 25mg/kg/hr IV x 15 min followed by 50mg/kg/hr if no allergic reactions
- Stop infusion after total of 100mg/kg infused
- BabyBIG obtained through CDC or local Department of Health
Inhalational Botulism
- Equine Serum Botulism Antitoxin
- only for patients > 1yo
- Antitoxin obtained through CDC or local Department of Health
Wound Botulism
- Individualize therapy with ID consultant
- Broad antibiotic coverage same as for Necrotizing fasciitis while awaiting wound cultures