Ketoconazole: Difference between revisions
| Line 31: | Line 31: | ||
==Adverse Reactions== | ==Adverse Reactions== | ||
===Serious=== | ===Serious=== | ||
*Hepatotoxicity | |||
*Adrenal insufficiency | |||
*Hypersensitivity reaction | |||
*Anaphylaxis | |||
*Thrombocytopenia | |||
*Leukopenia | |||
*Hemolytic Anemia | |||
===Common=== | ===Common=== | ||
Revision as of 01:13, 17 September 2015
Administration
- Type: Antifungal
- Dosage Forms:
- Routes of Administration: PO, topical
- Common Trade Names:
Adult Dosing
- Fungal infxns
- 200-400 mg PO qday
- Prostate cancer
- 400 mg PO q8h
Pediatric Dosing
- Fungal infxns (2 years and up)
- 3.3-6.6 mg/kg PO qday
Special Populations
Renal Dosing
- Adult: no adjustment
- Pediatric: no adjustment
Hepatic Dosing
- Adult: contraindicated in liver disease
- Pediatric: contraindicated in liver disease
Contraindications
- Allergy to class/drug
Adverse Reactions
Serious
- Hepatotoxicity
- Adrenal insufficiency
- Hypersensitivity reaction
- Anaphylaxis
- Thrombocytopenia
- Leukopenia
- Hemolytic Anemia
Common
Pharmacology
- Half-life:
- Metabolism:
- Excretion: