Zika virus: Difference between revisions
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==Management== | ==Management== | ||
*Supportive care | |||
**Hydration and antipyretic | |||
**Avoid NSAIDs until dengue excluded (risk of hemorrhage)<ref>Dick GW, Kitchen SF, Haddow AJ. Zika virus. I. Isolations and serological specificity. Trans R Soc Trop Med Hyg. 1952; 46(5): 509-20. PMID: 12995440</ref> | |||
*Avoid travelling to endemic areas if pregnant | |||
==Complications== | ==Complications== | ||
Revision as of 02:05, 16 February 2016
Background
- First reported case in US on Jan 13,2016 in patient who returned to Houston,TX after traveling to Latin America[1]
- Transmitted to humans through[2]:
- Travel history is key. Regions with active transmission include[5]:
- Africa
- Carribean
- Central America/Mexico
- Pacific Islands
- South America
Clinical Features[6]
- 80% of patients are asymptomatic
- Prodromal sx
- Fever, rash, joint pain, conjunctivitis
- After incubation period of 2-7 days
Differential Diagnosis
Fever in traveler
- Normal causes of acute fever!
- Malaria
- Dengue
- Leptospirosis
- Typhoid fever
- Typhus
- Viral hemorrhagic fevers
- Chikungunya
- Yellow fever
- Rift valley fever
- Q fever
- Amebiasis
- Zika virus
- Papules
- Insect bites
- Scabies
- Seabather's eruption
- Cercarial dermatitis (Swimmer's Itch)
- Macular
- Sub Q Swelling and Nodules
- Ulcers
- Tropical pyoderma
- Leishmaniasis
- Mycobacterium marinum
- Buruli ulcer
- Dracunculiasis (Guinea Worm disease)
- Linear and Migratory Lesions
- Cutaneous larvae migrans
- Photodermatitis
See also domestic U.S. ectoparasites
Diagnosis
- Clinical diagnosis
- Testing via PCR and IgM antibody assays via CDC or health department
- Reportable disease[7]
Management
- Supportive care
- Hydration and antipyretic
- Avoid NSAIDs until dengue excluded (risk of hemorrhage)[8]
- Avoid travelling to endemic areas if pregnant
Complications
- Possible epidemiologic associations between Zika virus infection and:
- Adverse fetal outcomes (congenital microcephaly)
- Guillan-Barre syndrome[9]
Disposition
See Also
External Links
References
- ↑ Faccini-Martínez ÁA, Botero-García CA, Benítez-Baracaldo FC, Pérez-Díaz CE. With regard about the case of Dengue, Chikungunya and Zika co-infection in a patient from Colombia. J Infect Public Health. 2016. PMID: 26837723
- ↑ Hayes EB. Zika virus outside Africa. Emerg Infect Dis. 2009;15:1347–50.
- ↑ Musso D, Roche C, Robin E, Nhan T, Teissier A, Cao-Lormeau VM. Potential sexual transmission of Zika virus. Emerg Infect Dis. 2015; 21(2): 359-61. PMID: 25625872
- ↑ Musso D, Nhan T, Robin E, et al. Potential for Zika virus transmission through blood transfusion demonstrated during an outbreak in French Polynesia, November 2013 to February 2014. Euro Surveill. 2014; 19(14): . PMID: 24739982
- ↑ CDC: Zika Travel Information
- ↑ CDC: Zika Virus: Clinical evaluation and disease
- ↑ CDC: National Notifiable Diseases Surveillance System (NNDSS)
- ↑ Dick GW, Kitchen SF, Haddow AJ. Zika virus. I. Isolations and serological specificity. Trans R Soc Trop Med Hyg. 1952; 46(5): 509-20. PMID: 12995440
- ↑ European Centre for Disease Prevention and Control. Rapid risk assessment: Zika virus epidemic in the Americas: potential association with microcephaly and Guillain-Barré syndrome [PDF]. Stockholm, Sweden: European Centre for Disease Prevention and Control; 2015.