Chlorate toxicity
Revision as of 04:51, 10 April 2017 by Rossdonaldson1 (talk | contribs) (Rossdonaldson1 moved page Chlorates to Chlorate toxicity)
Background
- Potassium Chlorate, Barium Chlorate, and Sodium Chlorate are still in use today
- Fireworks, match heads, and weed killers
Mechanism of Toxicity
- Oxidizers and attackers of sulfhydryl groups
- Cause methemoglobin formation
Clinical Presentation
Differential Diagnosis
Diagnosis
- Based on clinical history and presence of methemoglobinemia
- No specific levels are available
Management
- Activated charcoal IS recommended
- Methylene blue for methemoglobinemia (1-2 mg/kg of 1% solution)
- Sodium thiosulfate IV may inactivate chlorate ions (anecdotal)
- Hemodialysis
- Supportive Care
Disposition
External Links
References
Olson, K. Poisoning and Drug Overdose, 1999.