EBQ:PEAPETT Study

incomplete Journal Club Article

Sharifi M et al.. "Pulseless electrical activity in pulmonary embolism treated with

thrombolysis (from the “PEAPETT” study)". American Journal of Emergency Medicine. 2016. 34:1963-1967.
PubMed Full text

Clinical Question

Does low dose tissue plasminogen activator (tPA) improve survival in patients with pulseless electrical activity and cardiopulmonary arrest due to confirmed pulmonary embolism?


Conclusion

Rapid administration of 50mg of tPA is safe and effective in achieving ROSC in patients with PEA due to massive pulmonary embolism leading to increased survival and reduction of pulmonary artery pressures

Major Points

Study Design

Population

Patient Demographics

Inclusion Criteria

Exclusion Criteria

Interventions

Outcomes

Primary Outcome

Secondary Outcomes

Subgroup analysis

Criticisms & Further Discussion

External Links

See Also

Funding

References

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