Template:Cellulitis antibiotics

Tailor antibiotics by regional antibiogram

Outpatient

• 5 day treatment duration
  • Cephalexin 500mg PO q6hrs OR
    • Add DS 1 tab PO BID if MRSA suspected
  • Clindamycin 450mg PO TID covers Strep and Staph

Pediatric Outpatient

• Cephalexin 25-50mg/kg/day PO divided q6-8h (max 500mg/dose) OR
  • Add 8-12mg/kg/day (TMP) PO divided BID if MRSA suspected
• Clindamycin 30-40mg/kg/day PO divided TID (max 1.8g/day)

Inpatient

• Vancomycin 20mg/kg IV q12hrs OR
• Clindamycin 600mg IV q8hrs OR
• Linezolid 600mg IV q12hrs OR
• Daptomycin 4mg/kg IV once daily

Pediatric Inpatient

• Vancomycin 15mg/kg IV q6hrs OR
• Clindamycin 10-13mg/kg IV q8hrs (max 900mg/dose) OR
• Linezolid <12yr: 10mg/kg IV q8hrs; >12yr: 600mg IV q12hrs

Saltwater related cellulitis

• Doxycycline 100mg PO/IV q12hrs daily + Cefepime 1g IV q12hrs x 10 days
• Ciprofloxacin 400mg IV q12hrs x 10 days

Freshwater related cellulitis

• Ciprofloxacin 500mg PO q12hrs x 10 days
• TMP/SMX 2 DS tablets PO q12hrs x 10 days
• Ceftriaxone 1g (50mg/kg) IV q24hrs