Gold toxicity

Background

  • Gold is sometimes administered (as gold sodium thiomalate or Auranofin) IM/IV to treat rheumatoid arthritis and other autoimmune diseases
  • Use limited by significant adverse effect profile, including toxicity, and need for close monitoring

Clinical Features

Differential Diagnosis

Heavy metal toxicity

Evaluation

  • CBC, BMP, LFTs, UA
  • Assess for alternative diagnoses

Management

  • Supportive care
  • Most symptoms improve with cessation of gold therapy

Disposition

See Also

External Links

References

  • UpToDate, Tintinalli's

Authors:

Claire