Template:Brain abscess antibiotics

Otogenic source

• Cefotaxime 2gm IV q6hr + 500mg IV q6hr

Sinogenic or odontogenic source

• Cefotaxime 2gm IV q6hr + metronidazole 500mg IV q6hr

Penetrating trauma or neurosurgical procedures

• Vancomycin 15mg/kg IV q12hr + 2gm IV q8hr

Hematogenous source

• Cefotaxime 2gm IV q6hr + metronidazole 500mg IV q6hr

No obvious source

• Cefotaxime 2gm IV q6hr + metronidazole 500mg IV q6hr

Pediatric

• Cefotaxime 50mg/kg IV q6hrs (max 2g/dose) + Metronidazole 7.5mg/kg IV q6hrs (max 500mg)
• If post-surgical/trauma: Vancomycin 15mg/kg IV q6hrs + Ceftazidime 50mg/kg IV q8hrs (max 2g/dose)