Template:Cholangitis antibiotics

Coverage is targeted at E. coli, Enterococcus, Bacteroides, and Clostridium (anaerobic)

• Metronidazole 500mg IV q8hrs PLUS Ciprofloxacin 400mg IV q12hrs
• Piperacillin/Tazobactam 4.5g IV q8hrs
• Imipenem/Cilastatin 500mg IV q6hrs
• Doripenem 500mg IV q8hrs
• Meropenem 1g IV q8hrs

• Expand coverage for MRSA if severe sepsis or septic shock
  • Vancomycin 15-20mg/kg PLUS any of the above options