Template:Mastitis antibiotic

Treatment directed at S. aureus and Strep and E. coli

• Uncomplicated mastitis → 10 days of antibiotics (regardless of MRSA suspicion)
• Dicloxacillin 500mg PO q6hrs, considered first line if breastfeeding given safety for infant OR
• Cephalexin 500mg PO q6hrs OR
  • Add TMP/SMX 2DS tabs PO q12hrs if suspect MRSA
• Clindamycin 450mg PO q8hrs (also provides MRSA coverage) OR
• Amoxicillin/Clavulanate 875mg PO q12hrs OR
• Azithromycin 500mg PO x1 on day 1, then 250mg PO daily for days 2-5

Levine BL. 2011 EMRA Antibiotic Guide. EMRA. Pg 78.