Template:PID antibiotics

No sexual activity for 2 weeks;
Treat all partners who had sex with patient during previous 60 days prior to symptom onset

Outpatient Options

Alternative Outpatient Options

  • Historically the following regimens were acceptable but with the emerging resistance patterns use the following with caution.[5]
  • Ceftriaxone 250mg IM x1 + 1 g of azithromycin per week, x 2 weeks[6] +/- metronidazole based on above criteria
    • A single randomized controlled trial shows that azithromycin is superior to doxycycline even when compliance in taking doxycycline is excellent (98.2% vs 87.5%)[6]

Inpatient

  • Hayes BD. Trick of the Trade: IV ceftriaxone for gonorrhea. October 9th, 2012 ALiEM. https://www.aliem.com/2012/10/trick-of-trade-iv-ceftriaxone-for/. Accessed October 23, 2018.
  • Update to CDC's Treatment Guidelines for Gonococcal Infection, 2020 https://www.cdc.gov/mmwr/volumes/69/wr/mm6950a6.htm
  • Ness RB et al. Effectiveness of inpatient and outpatient treatment strategies for women with pelvic inflammatory disease: results from the Pelvic Inflammatory Disease Evaluation and Clinical Health (PEACH) Randomized Trial. Am J Obstet Gynecol 2002;186:929–37
  • CDC PID Treatment http://www.cdc.gov/std/treatment/2010/pid.htm
  • Update to CDC's Treatment Guidelines for Gonococcal Infection, 2020 https://www.cdc.gov/mmwr/volumes/69/wr/mm6950a6.htm
  • 6.0 6.1 Savaris RF. et al. Comparing ceftriaxone plus azithromycin or doxycycline for pelvic inflammatory disease: a randomized controlled trial. Obstet Gynecol. 2007 Jul;110(1):53-60