Template:Platelet transfusion indications

Platelet Transfusion Thresholds

most if not all of the following thresholds are based on weak recommendations with low quality evidence^[1]

<50K if planned lumbar puncture or neurosurgical procedure^[2]
<20K if planned for central venous catheter placement (preference toward compressible site), or febrile patient
<10K in asymptomatic patients (unless due to ITP, TTP, or HIT)

There are no firm recommendations for transfusion thresholds in acute traumatic bleeding but many providers will opt for a goal of 100K, especially if there is evidence of ICH

↑ Kaufman, R. et al. Platelet Transfusion: A Clinical Practice Guideline From the AABB. Annals of Internal Medicine. 2015. Vol 162. No. 3 205-214 Full Text
↑ Shuoyan, N. et al. Safety of Lumbar Punctures in Adult Oncology Patients with Thrombocytopenia. Blood 2015 126:1141

[1] Kaufman, R. et al. Platelet Transfusion: A Clinical Practice Guideline From the AABB. Annals of Internal Medicine. 2015. Vol 162. No. 3 205-214 Full Text

[2] Shuoyan, N. et al. Safety of Lumbar Punctures in Adult Oncology Patients with Thrombocytopenia. Blood 2015 126:1141

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