Template:Rocky Mountain Spotted Fever antibiotics

  • Doxycycline 100 mg BID for 5-7 days[1]
    • Indicated also in children at 2.2mg/kg BID
  • Chloramphenicol (CAM) 50-100 mg/kg/day div Q6hr (Max dose = 4g/day)
    • Preferred agent in pregnancy. May cause aplastic anemia and Grey baby syndrome, more common in near term or 3rd trimester[2]
    • Consideration should be made for doxycycline over CAM in the 3rd trimester
  • Shandera WX, Roig IL: Viral & Rickettsial Infections, in Papadakis MA, McPhee SJ (eds): Current Medical Diagnosis and Treatment, ed 52. USA, McGraw-Hill, 2013, (Ch) 32: p 1412-1413.
  • http://www.cdc.gov/rmsf/