Template:Yersinia antibiotics

Postexposure Prophylaxis

• Doxycycline 100mg (2.2mg/kg) PO q12hrs OR
• Ciprofloxacin 500mg (20mg/kg) PO q12hrs OR
• Chloramphenicol 25mg/kg PO q6hrs
  • only if age > 2

Active Disease

• Gentamicin 5mg/kg IV/IM once daily x 10 days OR
• Ciprofloxacin 500mg (20mg/kg) PO q12hrs x 10 days OR
• Doxycycline 200mg (2.2mg/kg) PO/IV daily
• Streptomycin 1g IM q12h x10 days; Maximum dose: 2 g/day (adjust dose based on serum levels)
• Streptomycin 15mg/kg IM q12h x10 days; Maximum dose: 2 g/day (adjust dose based on serum levels)

Pediatric

• Gentamicin 2.5mg/kg IV/IM q8hrs x 10 days
• Doxycycline 2.2mg/kg PO/IV q12hrs (max 100mg/dose)
• Ciprofloxacin 15mg/kg PO q12hrs (max 500mg/dose)
• Chloramphenicol 25mg/kg PO/IV q6hrs (max 4g/day); age >2 only