Tocilizumab

Administration

• Type: IL-6 antagonist
• Dosage Forms:
• Routes of Administration:
• Common Trade Names:

Adult Dosing

COVID

• 8 mg/kg actual body weight (up to 800 mg) administered as a single IV dose

Special Populations

Renal Dosing

• Adult:
• Pediatric:

Hepatic Dosing

• Adult:
• Pediatric:

Contraindications

• Allergy to class/drug

Pharmacology

• Half-life:
• Metabolism:
• Excretion:

Comments

• Trials show that may improved survival and other clinical outcomes in patients in admitted severe disease
• In clinical trials, a third of the participants received a second dose of tocilizumab 8 hours after the first dose if no clinical improvement was observed.