Ulipristal

Administration

  • Type: Contraceptive
  • Dosage Forms:
  • Routes of Administration: Oral
  • Common Trade Names: ella

Adult Dosing

  • 30 mg PO once as soon as possible within 120 hours of unprotected intercourse or suspected contraceptive failure

Pediatric Dosing

  • Postpubertal adolescents: see above

Special Populations

Contraindications

  • Allergy to class/drug
  • Pregnancy

Adverse Reactions

Serious

Common

  • Nausea, abdominal pain
  • Headache

Pharmacology

  • Half-life: 26-38h
  • Metabolism: Hepatic via CYP3A4
  • Excretion:

Mechanism of Action

  • Prevents progesterone from binding to progesterone receptor, thereby inhibiting or delaying ovulation

Comments

See Also

References

Authors:

Claire