Vecuronium

General

Adult Dosing

  • Not recommended for RSI
  • 0.15mg/kg IV based on ideal body weight, can prime with 0.01mg/kg IV

Pediatric Dosing

  • Not recommended for RSI

Special Populations

  • Pregnancy Rating: C
  • Lactation: Infant risk cannot be ruled out
  • Renal Dosing
    • Adult
    • Pediatric
  • Hepatic Dosing
    • Adult
    • Pediatric

Contraindications

  • Allergy to class/drug

Adverse Reactions

Serious

Common

Pharmacology

  • Half-life: Varies, from 30-60 minutes
  • Metabolism: Hepatic
  • Excretion: Renal
  • Mechanism of Action: Non-depolarizing neuromuscular blocking agent. Long duration with slow onset. Competes for cholinergic receptors at the motor end-plate. Acetylcholinesterase inhibitors like those found in organophosphates antagonize this action

See Also

References

Micromedex