Fever of unknown origin (peds): Difference between revisions
ClaireLewis (talk | contribs) |
No edit summary |
||
| (2 intermediate revisions by one other user not shown) | |||
| Line 1: | Line 1: | ||
{{Peds top}} [[fever of unknown origin]] | |||
==Background== | ==Background== | ||
*Prolonged fever of unknown origin without identified cause generally has favorable prognosis. | *Prolonged fever of unknown origin without identified cause generally has favorable prognosis. | ||
| Line 36: | Line 37: | ||
***[[Blastomycosis]] | ***[[Blastomycosis]] | ||
***[[Histoplasmosis]] | ***[[Histoplasmosis]] | ||
**[[Parasitic | **[[Parasitic infection|Parasitic]] | ||
***[[Malaria]] | ***[[Malaria]] | ||
***[[Toxoplasmosis]] | ***[[Toxoplasmosis]] | ||
| Line 51: | Line 52: | ||
**[[Lymphoma]] | **[[Lymphoma]] | ||
**[[Neuroblastoma (peds)|Neuroblastoma]] | **[[Neuroblastoma (peds)|Neuroblastoma]] | ||
**[[Wilms]] | **[[Wilms' tumor]] | ||
*'''Drug Induced''' | *'''Drug Induced''' | ||
**[[Antibiotics]] | **[[Antibiotics]] | ||
Latest revision as of 23:08, 28 November 2019
This page is for pediatric patients. For adult patients, see: fever of unknown origin
Background
- Prolonged fever of unknown origin without identified cause generally has favorable prognosis.
Clinical Features
- Original definition[1]
- Fever >38.3 C on several occasions
- Lasting for at least 3 weeks
- No clear diagnosis after 1 week inpatient workup
- Newer definition[2] - "Prolonged fever" with:
- 3 outpatient visits without identifying a cause or
- 3 inpatient days without identifying a cause or
- 1 week of “intelligent and invasive” ambulatory investigation
Differential Diagnosis
- Infection
- Bacterial
- Adenitis
- Endocarditis
- Mastoiditis
- Occult abscess
- Pyelonephritis
- Sinusitis
- Tb
- Mycoplasmal
- Chlamydial
- Rickettsial
- Viral
- Fungal
- Parasitic
- Bacterial
- Non-infectious Inflammatory
- Juvenile idiopathic arthritis
- SLE
- Regional enteritis
- Rheumatic fever
- Ulcerative colitis
- Vasculitis
- Malignancy
- Drug Induced
- Misc
- AIDS
- CNS dysfunction
- Environmental hyperthermia
- Factitious
- Familial dysautonomia
- Kawasaki
- PE
- Serial infections
- Thyrotoxicosis
Evaluation
- Clinical (preliminary) diagnosis
Management
- Treat underlying cause (once identified)
- Empiric treatment generally not recommended
Disposition
- Frequently admitted for workup