Anticonvulsants: Difference between revisions
| Line 33: | Line 33: | ||
|| Over 10 minutes || Any || Choose alternate drug if on phenytoin at home; may decrease BP/HR | || Over 10 minutes || Any || Choose alternate drug if on phenytoin at home; may decrease BP/HR | ||
|- | |- | ||
| [[Valproic acid]] || * | | [[Valproic acid]] || | ||
40 mg/kg/dose IV/IO | *40 mg/kg/dose IV/IO | ||
*MAX: 3000 mg/dose | *MAX: 3000 mg/dose | ||
|| Over 10 minutes || >2 years || Caution in patients with liver dysfunction, mitochondrial disease, urea disorder, thrombocytopenia, or unexplained developmental delay | || Over 10 minutes || >2 years || Caution in patients with liver dysfunction, mitochondrial disease, urea disorder, thrombocytopenia, or unexplained developmental delay | ||
Revision as of 20:40, 19 October 2022
- Carbamazepine (Tegretol)
- Clobazam (Onfi)
- Diazepam (Valium)
- Ethosuximide
- Fosphenytoin
- Gabapentin (Neurontin)
- Lacosamide (Vimpat)
- Lamotrigine (Lamictal)
- Levetiracetam (Keppra)
- Lorazepam (Ativan)
- Midazolam (Versed)
- Oxcarbazepine (Trileptal)
- Pentobarbital
- Phenobarbital
- Phenytoin (Dilantin)
- Propofol
- Topiramate (Topamax)
- Valproate (Depakote)
- Zonisamide
Pediatric Anticonvulsants Table
| Drug | Dose | Infusion Rate | Age | Comments/Cautions |
|---|---|---|---|---|
| Levetiracetam |
|
Over 5 minutes | Any | Most commonly used agent |
| Fosphenytoin |
|
Over 10 minutes | Any | Choose alternate drug if on phenytoin at home; may decrease BP/HR |
| Valproic acid |
|
Over 10 minutes | >2 years | Caution in patients with liver dysfunction, mitochondrial disease, urea disorder, thrombocytopenia, or unexplained developmental delay |
| Phenytoin |
|
Over 20 minutes | Any | Choose alternate drug if on phenytoin at home; may decrease BP/HR |
| Phenobarbital |
|
Over 20 minutes | <6 months | Respiratory depression, especially in combination with benzos |