Diuretics: Difference between revisions
Ostermayer (talk | contribs) |
(Add References section) |
||
| (2 intermediate revisions by one other user not shown) | |||
| Line 3: | Line 3: | ||
===High ceiling/[[loop diuretic]]=== | ===High ceiling/[[loop diuretic]]=== | ||
''Inhibit Na+/K+/2Cl symporter in ascending limb of loop of Henle, preventing reabsorption and thereby increasing urinary excretion of sodium, chloride, and potassium | ''Inhibit Na+/K+/2Cl symporter in ascending limb of loop of Henle, preventing reabsorption and thereby increasing urinary excretion of sodium, chloride, and potassium | ||
{{#ask: [[Loop diuretic]] | |||
|?Has DrugName= | |||
|mainlabel=- | |||
|headers=hide | |||
|format=ul | |||
|valuesep=</li><li> | |||
}} | |||
*40mg furosemide = 20 mg torsemide = 1mg bumetanide = 50 mg ethacrynic acid | *40mg furosemide = 20 mg torsemide = 1mg bumetanide = 50 mg ethacrynic acid | ||
| Line 32: | Line 35: | ||
==See Also== | ==See Also== | ||
*[[Antihypertensive medications]] | *[[Antihypertensive medications]] | ||
==References== | |||
<references/> | |||
[[Category:Pharmacology]] | [[Category:Pharmacology]] | ||
Latest revision as of 09:10, 22 March 2026
Types
High ceiling/loop diuretic
Inhibit Na+/K+/2Cl symporter in ascending limb of loop of Henle, preventing reabsorption and thereby increasing urinary excretion of sodium, chloride, and potassium
- 40mg furosemide = 20 mg torsemide = 1mg bumetanide = 50 mg ethacrynic acid
Thiazides
Act on the distal convoluted tubule and inhibit the sodium-chloride symporter
Carbonic anhydrase inhibitors
Inhibit the enzyme carbonic anhydrase in the proximal convoluted tubule
Potassium-sparing diuretics
- Aldosterone antagonists
- Epithelial sodium channel blockers:
Osmotic diuretics
Increase osmolality and work primarily by expanding extracellular fluid and plasma volume, therefore increasing blood flow to the kidneys
- Mannitol
- Glucose (e.g. during hyperglycemia)