Coagulopathy (main): Difference between revisions

Latest revision as of 18:15, 17 February 2021

Primary hemostasis: damage to endothelial basement membrane and formation of platelet plug
Secondary hemostasis: coagulation cascade

Coagulation cascade

Authors:

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-==DDX==
+==Background==
-*[[Vitamin K Deficiency]]
+*Primary hemostasis: damage to endothelial basement membrane and formation of platelet plug
-*[[Warfarin (Coumadin)]]
+*Secondary hemostasis: coagulation cascade
-*[[Heparin]]
+[[File:Coagulation cascade.png|thumbnail|Coagulation cascade]]
-*[[Lovenox]]
-*[[DIC]]
-*[[Hemophilia]]
-*[[Factor VIII Inhibitor]]
-==[[Lupus Anticoagulan]]t==
+==Clinical Features==
-#(rare)
+*Spontaneous [[hemorrhage|bleeding]]
-#warfarin or ASA
+*Bleeding out of proportion
+*Swollen joints
+*[[Epistaxis]]
+*Bleeding gums
+*[[vaginal Bleed Non-Pregnant|Menometrorrhagia]]
+*Easy bruising/[[petechiae]]
+*[[Hematuria]]
-==[[Liver Disease Induced Coagulopathy]]==
+==Differential Diagnosis==
+{{Increased bleeding DDX}}
-==[[Renal Disease Induced Coagulopathy]]==
+===Increased Clotting===
+{{Increased clotting DDX}}
-==Managment==
+==Management==
-*[[Warfarin (Coumadin) Reversal]]
+*[[Bleeding Treatments]]
+*[[Procedures in patients with coagulopathies]]
+*[[Anticoagulant reversal]] (known medications)
+**[[Warfarin (Coumadin) Reversal]]
+**[[Dabigatran (Pradaxa) Reversal]]
+**[[Rivaroxaban reversal]]
+**[[Unfractionated heparin reversal]]
+*[[Anti-platelet agent reversal]]
 ==See Also==
-*[[Bleeding Treatments]]
+*[[Transfusions]]
+*[[Idarucizumab]]
-==Source==
+*[[Procedures in patients with coagulopathies]]
-*Tintinalli
-*UpToDate
+==References==
+<references/>
 [[Category:Heme/Onc]]