Coagulopathy (main): Difference between revisions

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==DDX==
==Background==
*[[Vitamin K Deficiency]]
*Primary hemostasis: damage to endothelial basement membrane and formation of platelet plug
*[[Warfarin (Coumadin)]]
*Secondary hemostasis: coagulation cascade
*[[Heparin]]
[[File:Coagulation cascade.png|thumbnail|Coagulation cascade]]
*[[Lovenox]]
*[[DIC]]
*[[Hemophilia]]
*[[Factor VIII Inhibitor]]
*[[Lupus Anticoagulan]]t]]
*[[Liver Disease Induced Coagulopathy]]
*[[Renal Disease Induced Coagulopathy]]


==Managment==
==Clinical Features==
*Spontaneous [[hemorrhage|bleeding]]
*Bleeding out of proportion
*Swollen joints
*[[Epistaxis]]
*Bleeding gums
*[[vaginal Bleed Non-Pregnant|Menometrorrhagia]]
*Easy bruising/[[petechiae]]
*[[Hematuria]]
 
==Differential Diagnosis==
{{Increased bleeding DDX}}
 
===Increased Clotting===
{{Increased clotting DDX}}
 
==Management==
*[[Bleeding Treatments]]
*[[Bleeding Treatments]]
*[[Warfarin (Coumadin) Reversal]]
*[[Procedures in patients with coagulopathies]]
*[[Anticoagulant reversal]] (known medications)
**[[Warfarin (Coumadin) Reversal]]
**[[Dabigatran (Pradaxa) Reversal]]
**[[Rivaroxaban reversal]]
**[[Unfractionated heparin reversal]]
*[[Anti-platelet agent reversal]]


==See Also==
==See Also==
*[[Transfusions]]
*[[Idarucizumab]]
*[[Procedures in patients with coagulopathies]]


 
==References==
==Source==
<references/>
*Tintinalli
*UpToDate
 
[[Category:Heme/Onc]]
[[Category:Heme/Onc]]

Latest revision as of 18:15, 17 February 2021

Background

  • Primary hemostasis: damage to endothelial basement membrane and formation of platelet plug
  • Secondary hemostasis: coagulation cascade
Coagulation cascade

Clinical Features

Differential Diagnosis

Coagulopathy

Platelet Related

Factor Related

Increased Clotting

Management

See Also

References