Urethritis in men: Difference between revisions

 
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==Background==
==Background==
[[File:Prostatelead.jpg|thumb|Urethral anatomy]]
{{UTI types}}
{{UTI types}}


==Clinical Features==
==Clinical Features==
[[File:SOA-Chlamydia-trachomatis-male.jpg|thumb|[[Chlamydia trachomatis]] on male GU exam consistent with urethritis.]]
*Dysuria
*Dysuria
*Urethral discharge
*Urethral discharge
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==Evaluation==
==Evaluation==
===Workup===
===Workup===
*UA
*[[Urinalysis]]
*Urine GC/chlamydia
*Urine GC/chlamydia
*Consider M. genitalium and trichomonas testing


===Diagnosis===
===Diagnosis===
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==Management==
==Management==
''Initial antimicrobial treatment is typically empiric, depending on risk for gonococcal versus nongonococcal urethritis''
{{Male urethritis treatment}}
 
===[[Gonococcal]]===
''Will also treat [[chlamydia]]''
*[[Ceftriaxone]] 250 mg IM x 1, '''PLUS'''
*[[Azithromycin]] 1 gm PO x 1
 
===Nongonococcal===
''[[Chlamydia]] most likely pathogen''
*[[Azithromycin]] 1 gm PO x 1, '''OR'''
*[[Doxycycline]] 100 mg  PO BID x 7 days
 
===Recurrent or Persistent===
''Target [[M. genitalium]]''
*[[Azithromycin]] 1 gm PO x 1 (if not administered in the initial regimen), '''OR'''
*[[Moxifloxacin]] 400 mg daily x 7 days (if the initial failed regimen included azithromycin)
 
''Consider coverage of [[T. vaginalis]], among men who have sex with women''
*Metronidazole 2 gm PO x 1, '''OR'''
*Tinidazole 2 gm PO x 1


==Disposition==
==Disposition==

Latest revision as of 16:43, 23 April 2025

Background

Urethral anatomy

Genitourinary infection

(1) Human urinary system: (2) kidney; (3) renal pelvis; (4) ureter; (5) urinary bladder (6) urethra.
Additional structures: (7) adrenal gland; (8) renal artery and vein; (9) inferior vena cava; (10) abdominal aorta; (11) common iliac artery and vein; (12) liver; (13) large intestine; (14) pelvis.

"UTI" frequently refers specifically to acute cystitis, but may also be used as a general term for all urinary infections; use location-specific diagnosis.

Clinical Features

Chlamydia trachomatis on male GU exam consistent with urethritis.
  • Dysuria
  • Urethral discharge

Differential Diagnosis

Dysuria

Evaluation

Workup

  • Urinalysis
  • Urine GC/chlamydia
  • Consider M. genitalium and trichomonas testing

Diagnosis

  • Typically initially a clinical diagnosis with empiric treatment

Management

Uncomplicated Infection

Treatment to cover both gonorrhea and chlamydia Typically, treatment for both gonorrhea and chlamydia is indicated, if one entity is suspected.

Standard


Ceftriaxone contraindicated

^Additional chlamydia coverage only needed if treated with cefixime only

Partner Treatment

Recurrent or Persistent

Target M. genitalium

Consider coverage of trichomonas, among men who have sex with women

Disposition

  • Outpatient

See Also

References