CMV colitis: Difference between revisions
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==Background== | ==Background== <!--T:1--> | ||
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*CMV is part of the Herpesviridae family | *CMV is part of the Herpesviridae family | ||
*50-80% of the world's population is seropositive for CMV | *50-80% of the world's population is seropositive for CMV | ||
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==Clinical Features== | ==Clinical Features== <!--T:3--> | ||
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*[[Special:MyLanguage/Fever|Fever]] | *[[Special:MyLanguage/Fever|Fever]] | ||
*Anorexia | *Anorexia | ||
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==Differential Diagnosis== | ==Differential Diagnosis== <!--T:5--> | ||
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==Evaluation== | ==Evaluation== <!--T:6--> | ||
==Management== | ==Management== <!--T:7--> | ||
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==Disposition== | ==Disposition== <!--T:8--> | ||
==See Also== | ==See Also== <!--T:9--> | ||
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*[[Special:MyLanguage/Cytomegalovirus (CMV) infection|Cytomegalovirus (CMV) infection]] | *[[Special:MyLanguage/Cytomegalovirus (CMV) infection|Cytomegalovirus (CMV) infection]] | ||
==External Links== | ==External Links== <!--T:11--> | ||
==References== | ==References== <!--T:12--> | ||
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<references/> | <references/> | ||
[[Category:ID]] [[Category:GI]] | [[Category:ID]] [[Category:GI]] | ||
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Latest revision as of 12:25, 7 January 2026
Background
- CMV is part of the Herpesviridae family
- 50-80% of the world's population is seropositive for CMV
- Causes a mild or undetectable infection in immunocompetent hosts
- Severe systemic illness is found in immunosuppressed hosts
Clinical Features
- Fever
- Anorexia
- Malaise
- Abdominal pain, Abdominal distention, constipation
- Nausea/vomiting
- Chronic watery diarrhea
- Bloody diarrhea
- Worsening symptoms of inflammatory bowel disease
- Weight loss
- Dehydration
Differential Diagnosis
Colitis
- Viral gastroenteritis
- Bacterial gastroenteritis
- Campylobacter infections
- Clostridium difficile colitis
- Colon cancer
- Crohn disease
- Cryptosporidiosis
- Mycobacterium Avium-Intracellulare
- Toxic megacolon
- Ulcerative colitis
- Ischemic bowel disease (e.g. mesenteric ischemia, strangulated hernia)
- Pseudomembranous enterocolitis
- Lymphoma
- Ileocecal amebiasis
- Sarcoidosis
- Yersinia
- Campylobacter
CMV Diseases
Evaluation
Management
- Ganciclovir 5mg/kg IV q12hrs x 21 days (or until resolution of symptoms)
- Foscarnet 90mg/kg IV q12hrs daily x 21 days (or until resolution of symptoms)
Disposition
See Also
