Template:Animal bite antibiotics: Difference between revisions
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''Coverage for [[Pasteurella]], [[Strep]], and [[Staph]]'' | ''Coverage for [[Pasteurella]], [[Strep]], and [[Staph]]'' | ||
*'''Consider for high-risk wounds''' | *'''Consider for high-risk wounds''' | ||
**wounds reaching the level of the muscle/tendon, wounds to the hand, violation of bone or joint capsule, immunocompromised hosts, wounds associated with significant local edema | **wounds reaching the level of the muscle/tendon, wounds to the hand<ref>EBQ:Antibiotic prophylaxis for mammalian bites</ref>, violation of bone or joint capsule, immunocompromised hosts, wounds associated with significant local edema | ||
*[[Amoxicillin/Clavulanate|Amoxicilin-clavulanate]] 875mg PO BID x 5-7 days OR<ref>Griego RD, Rosen T, Orengo IF, Wolf JE. Dog, cat, and human bites: a review. J Am Acad Dermatol. 1995;33:1019–29.</ref> | *[[Amoxicillin/Clavulanate|Amoxicilin-clavulanate]] 875mg PO BID x 5-7 days OR<ref>Griego RD, Rosen T, Orengo IF, Wolf JE. Dog, cat, and human bites: a review. J Am Acad Dermatol. 1995;33:1019–29.</ref> | ||
*[[Doxycycline]] 100mg PO daily x 14 days if penicillin allergic <ref>Talan DA, Citron DM, Abrahamian FM, Moran GJ, Goldstein EJ. Bacteriologic analysis of infected dog and cat bites. Emergency Medicine Animal Bite Infection Study Group. N Engl J Med. 1999;340:85–92.</ref> | *[[Doxycycline]] 100mg PO daily x 14 days if penicillin allergic <ref>Talan DA, Citron DM, Abrahamian FM, Moran GJ, Goldstein EJ. Bacteriologic analysis of infected dog and cat bites. Emergency Medicine Animal Bite Infection Study Group. N Engl J Med. 1999;340:85–92.</ref> | ||
Revision as of 12:22, 1 February 2017
Cat and Dog Bites
Coverage for Pasteurella, Strep, and Staph
- Consider for high-risk wounds
- wounds reaching the level of the muscle/tendon, wounds to the hand[1], violation of bone or joint capsule, immunocompromised hosts, wounds associated with significant local edema
- Amoxicilin-clavulanate 875mg PO BID x 5-7 days OR[2]
- Doxycycline 100mg PO daily x 14 days if penicillin allergic [3]
- Clindamycin 450mg (5mg/kg) PO q8hrs daily x7 days PLUS
- Ciprofloxacin 500mg PO q12hrs x 7 days OR
- TMP/SMX 2DS tabs (5mg/kg) PO q12hrs
Human Bites
All human bites should be strongly considered for antibiotic therapy.
Requires polymicrobial coverage for: S. aureus, Strep Viridans, Bacteroides, Coagulase-neg Staph, Eikenella, Fusobacterium, Cornebacterium, peptostreptococus
- Amoxicilin-clavulanate 875mg PO BID x 5-7days OR
- Clindamycin 450mg (5mg/kg) PO q8hrs daily x7 days PLUS
- Ciprofloxacin 500mg PO q12hrs x 7 days OR
- TMP/SMX 2DS tabs (5mg/kg) PO q12hrs
Mammalian Bites Severe Infections
- Ampicillin/Sulbactam 3g IV (50mg/kg IV) q 6hrs daily OR
- Cefoxitin 1g IV q8hrs (25mg/kg q6hrs) OR
- Pipericillin/Tazobactam 4.5g IV (80mg/kg IV) q8hrs OR
- Ceftriaxone 1g (50mg/kg IV) once + Metronidazole 500mg IV q8hrs OR
- Clindamycin 600mg IV q8hrs PLUS
- TMP/SMX 5mg/kg IV q12hrs OR
- Ciprofloxacin 400mg IV q12hrs OR
- ↑ EBQ:Antibiotic prophylaxis for mammalian bites
- ↑ Griego RD, Rosen T, Orengo IF, Wolf JE. Dog, cat, and human bites: a review. J Am Acad Dermatol. 1995;33:1019–29.
- ↑ Talan DA, Citron DM, Abrahamian FM, Moran GJ, Goldstein EJ. Bacteriologic analysis of infected dog and cat bites. Emergency Medicine Animal Bite Infection Study Group. N Engl J Med. 1999;340:85–92.