United States Antibiogram: Difference between revisions
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{| class="wikitable"
{| class="wikitable"
| align="center" style="background:#f0f0f0;"|'''Category'''
| align="center" style="background:#f0f0f0;"|'''Category'''
| align="center" style="background:#f0f0f0;"|'''Antibiotic'''
| align="center" style="background:#f0f0f0;"|'''Organism'''
| align="center" style="background:#f0f0f0;"|'''[[Strep. Group A, B, C, G]]'''
| align="center" style="background:#f0f0f0;"|'''[[Strep. Group A, B, C, G]]'''
| align="center" style="background:#f0f0f0;"|'''[[Strep. Pneumoniae]]'''
| align="center" style="background:#f0f0f0;"|'''[[Strep. Pneumoniae]]'''
| align="center" style="background:#f0f0f0;"|'''[[Viridans strep]]'''
| align="center" style="background:#f0f0f0;"|'''[[Viridans strep]]'''
| align="center" style="background:#f0f0f0;"|'''[[Strep. milleri]]'''
| align="center" style="background:#f0f0f0;"|'''[[Strep. anginosus gp]]'''
| align="center" style="background:#f0f0f0;"|'''[[Enterococcus faecalis]]'''
| align="center" style="background:#f0f0f0;"|'''[[Enterococcus faecalis]]'''
| align="center" style="background:#f0f0f0;"|'''[[Enterococcus faecium]]'''
| align="center" style="background:#f0f0f0;"|'''[[Enterococcus faecium]]'''
| align="center" style="background:#f0f0f0;"|'''Staph. aureus ([[MSSA]])'''
| align="center" style="background:#f0f0f0;"|'''[[MSSA]]'''
| align="center" style="background:#f0f0f0;"|'''Staph. aureus ([[MRSA]])'''
| align="center" style="background:#f0f0f0;"|'''[[MRSA]]'''
| align="center" style="background:#f0f0f0;"|'''Staph. aureus ([[CA-MRSA]])'''
| align="center" style="background:#f0f0f0;"|'''[[CA-MRSA]]'''
| align="center" style="background:#f0f0f0;"|'''[[Staph. Epidermidis]]'''
| align="center" style="background:#f0f0f0;"|'''[[Staph. Epidermidis]]'''
| align="center" style="background:#f0f0f0;"|'''[[C. jeikeium]]'''
| align="center" style="background:#f0f0f0;"|'''[[C. jeikeium]]'''
| align="center" style="background:#f0f0f0;"|'''[[L. monocytogenes]]'''
| align="center" style="background:#f0f0f0;"|'''[[L. monocytogenes]]'''
|-
|-
| [[Penicillins]]||[[Penicillin G]]||+||+||+/-||+||+||+/-||0||0||0||0||0||+
| [[Penicillins]]||[[Penicillin G]]||S||S||I||S||S||I||R||R||R||R||R||S
|-
|-
| ||[[Penicillin V]]||+||+||+/-||+||+||+/-||0||0||0||0||0||0
| ||[[Penicillin V]]||S||S||I||S||S||I||R||R||R||R||R||R
|-
|-
| Anti-Staphylocccal [[Penicillins]]||Methicillin||+||+||+/-||+||0||0||+||0||0||+||0||0
| ||[[Methicillin]]||S||S||I||S||R||R||S||R||R||S||R||R
|-
|-
| ||Nafcillin/Oxacillin||+||+||+/-||+||0||0||+||0||0||+||0||0
| ||[[Nafcillin]]/[[Oxacillin]]||S||S||I||S||R||R||S||R||R||S||R||R
|-
|-
| ||Dicloxacillin||+||+||+/-||+||0||0||+||0||0||+||0||0
| ||[[Cloxacillin]]/[[Diclox.]]||S||S||I||S||R||R||S||R||R||S||R||R
|-
|-
| Amino-[[Penicillins]]||[[AMP]]/[[Amox]]||+||+||+/-||+||+||+||0||0||0||0||0||+
| Amino-[[Penicillins]]||[[AMP]]/[[Amox]]||S||S||I||S||S||I||R||R||R||R||R||S
|-
|-
| ||[[Amox-Clav]]||+||+||+/-||+||+||+||+||0||0||0||0||
| ||[[Amox-Clav]]||S||S||I||S||S||S||S||R||R||R||R||X2
|-
|-
| ||[[AMP-Sulb]]||+||+||+/-||+||+||+||+||0||0||0||0||+
| ||[[AMP-Sulb]]||S||S||I||S||S||S||S||R||R||R||R||S
|-
|-
| Anti-Pseudomonal [[Penicillins]]||[[Ticar-Clav]]||+||+||+/-||+||+/-||+/-||+||0||0||+/-||0||
| Anti-Pseudomonal [[Penicillins]]||[[Ticarcillin]]||S||S||I||S||I||I||R||R||R||I||R||S
|-
|-
| ||[[Pip-Tazo]]||+||+||+/-||+||+||+/-||+||0||0||+||||
| ||[[Ticar-Clav]]||S||S||I||S||I||I||S||R||R||I||R||X2
|-
|-
| [[Carbapenems]]||Doripenem||+||+||+||+||+/-||0||+||0||0||+||||+
| ||[[Pip-Tazo]]||S||S||I||S||S||I||S||R||R||S||X1||X2
|-
|-
| ||[[Ertapenem]]||+||+||+||+||0||0||+||0||0||+||0||+/-
| ||Piperacillin||S||S||I||S||S||I||R||R||R||R||R||S
|-
|-
| ||[[Imipenem]]||+||+||+||+||+||+/-||+||0||0||+||0||+
| [[Carbapenems]]||Doripenem||S||S||S||S||I||R||S||R||R||S||X1||S
|-
|-
| ||[[Meropenem]]||+||+||+||+||+/-||0||+||0||0||+||||+
| ||[[Ertapenem]]||S||S||S||S||R||R||S||R||R||S||R||I
|-
|-
| Monobactam||[[Aztreonam]]||0||0||0||0||0||0||0||0||0||0||0||0
| ||[[Imipenem]]||S||S||S||S||S||I||S||R||R||S||R||S
|-
|-
| [[Fluroquinolones]]||[[Ciprofloxacin]]||+/-||+/-||0||0||^^||0||+||0||+/-||+||0||+
| ||[[Meropenem]]||S||S||S||S||I||R||S||R||R||S||X1||S
|-
|-
| ||[[Ofloxacin]]||+/-||+/-||0||0||^^||0||+||0||||+||0||0
| ||[[Aztreonam]]||R||R||R||R||R||R||R||R||R||R||R||R
|-
|-
| ||[[Levofloxacin]]||+||+||+||+||+||0||+||0||+/-||+||||+
| [[Fluroquinolones]]||[[Ciprofloxacin]]||I||I||R||R||^^||R||S||R||I||S||R||S
|-
|-
| ||[[Moxifloxacin]]||+||+||+||+||+||+/-||+||+/-||+/-||+||||+
| ||[[Ofloxacin]]||I||I||R||R||^^||R||S||R||X1||S||R||R
|-
|-
| ||Gemifloxacin||+||+||+||+||+||+/-||+||+/-||+/-||+||||+
| ||Pefloxacin||R||R||X1||X1||R||R||S||R||X1||S||X1||R
|-
|-
| ||Gatifloxacin||+||+||+||+||+||+/-||+||+/-||+/-||+||||+
| ||[[Levofloxacin]]||S||S||S||S||S||R||S||R||I||S||X1||S
|-
|-
| 1st G [[Cephalo]]||Cefazolin||+||+||+||||0||||+||0||0||+/-||0||0
| ||[[Moxifloxacin]]||S||S||S||S||S||I||S||I||I||S||X1||S
|-
|-
| 2nd G [[Cephalo]]||[[Cefotetan]]||+||+||+||||0||||+||0||0||+/-||0||0
| ||Gemifloxacin||S||S||S||S||S||I||S||I||I||S||X1||S
|-
|-
| ||[[Cefoxitin]]||+||+||+||||0||||+||0||0||+/-||0||0
| ||Gatifloxacin||S||S||S||S||S||I||S||I||I||S||X1||S
|-
|-
| ||[[Cefuroxime]]||+||+||+||||0||||+||0||0||+/-||0||0
| 1st G [[Cephalo]]||Cefazolin||S||S||S||X1||R||X1||S||R||R||I||R||R
|-
|-
| 3rd/4th G [[Cephalo]]||[[Cefotaxime]]||+||+||+||||0||||+||0||0||+/-||0||0
| 2nd G. [[Cephalo]]||[[Cefotetan]]||S||S||S||X1||R||X1||S||R||R||I||R||R
|-
|-
| ||Cefizoxime||+||+||+||||0||||+||0||0||+/-||0||0
| ||[[Cefoxitin]]||S||S||S||X1||R||X1||S||R||R||I||R||R
|-
|-
| ||[[CefTRIAXone]]||+||+||+||||0||||+||0||0||+/-||0||0
| ||[[Cefuroxime]]||S||S||S||X1||R||X1||S||R||R||I||R||R
|-
|-
| ||Ceftaroline||+||+||+||||+||||+||+||+||+||||
| 3rd/4th G. [[Cephalo]]||[[Cefotaxime]]||S||S||S||X1||R||X1||S||R||R||I||R||R
|-
|-
| ||[[CefTAZidime]]||+||+||+/-||||0||||+/-||0||0||+/-||0||0
| ||Cefizoxime||S||S||S||X1||R||X1||S||R||R||I||R||R
|-
|-
| ||[[Cefepime]]||+||+||+||||0||||+||0||0||+/-||||0
| ||[[CefTRIAXone]]||S||S||S||X1||R||X1||S||R||R||I||R||R
|-
|-
| Oral 1st G [[Cephalo]]||Cefadroxil||+||+||+||||0||||+||0||0||+/-||0||0
| ||Ceftaroline||S||S||S||X1||S||X1||S||S||S||S||X1||X1
|-
|-
| ||[[Cephalexin]]||+||+||+||||0||||+||0||0||+/-||0||0
| ||[[CefTAZidime]]||S||S||I||X1||R||X1||I||R||R||I||R||R
|-
|-
| Oral 2nd G [[Cephalo]]||Cefaclor||+||+||+||||0||||+||0||0||+/-||0||0
| ||[[Cefepime]]||S||S||S||X1||R||X1||S||R||R||I||||R
|-
|-
| ||Cefproxil||+||+||0||||0||||+||0||0||+/-||0||0
| Oral 1st G. [[Cephalo]]||Cefadroxil||S||S||S||X1||R||X1||S||R||R||I||R||R
|-
|-
| ||Cefuroxime||+||+||+||||0||||+||0||0||+/-||0||0
| ||[[Cephalexin]]||S||S||S||X1||R||X1||S||R||R||I||R||R
|-
|-
| Oral 3rd G [[Cephalo]]||Cefixime||+||+||+||||0||||0||0||0||0||0||0
| Oral 2nd G. [[Cephalo]]||Cefaclor/Loracarbef||S||S||S||X1||R||X1||S||R||R||I||R||R
|-
|-
| ||Ceftibuten||+||+/-||0||||0||||0||0||0||0||0||0
| ||Cefproxil||S||S||R||X1||R||X1||S||R||R||I||R||R
|-
|-
| ||Cefpodox/ Cefdinir/ Cefditoren||+||+||+||||0||||+||0||0||+/-||||0
| ||Cefuroxime axetil||S||S||S||X1||R||X1||S||R||R||I||R||R
|-
|-
| [[Aminoglycosides]]||[[Gentamicin]]||0||0||||||S||S||+||0||||+/-||0||S
| Oral 3rd G. [[Cephalo]]||Cefixime||S||S||S||X1||R||X1||R||R||R||R||R||R
|-
|-
| ||Tobramycin||0||0||||||S||0||+||0||||+/-||0||S
| ||Ceftibuten||S||I||R||X1||R||X1||R||R||R||R||R||R
|-
|-
| ||[[Amikacin]]||0||0||||||S||0||+||0||||+/-||0||S
| ||Cefpodox/Cefdinir/Cefditoren||S||S||S||X1||R||X1||S||R||R||I||X1||R
|-
|-
| ||[[Chloramphenicol]]||+||+||||||+/-||+/-||+/-||0||||0||0||+
| [[Aminoglycosides]]||[[Gentamicin]]||R||R||X1||X1||SS||SS||S||R||X1||I||R||SS
|-
|-
| ||[[Clindamycin]]||+||+||||||0||0||+||0||+/-||0||0||
| ||Tobramycin||R||R||X1||X1||SS||R||S||R||X1||I||R||SS
|-
|-
| [[Macrolides]]||Erythromycin||+/-||+||||||0||0||+/-||0||+/-||+/-||0||+
| ||[[Amikacin]]||R||R||X1||X1||SS||R||S||R||X1||I||R||SS
|-
|-
| ||[[Azithromycin]]||+/-||+||||||0||0||+||0||+/-||0||0||+
| ||[[Chloramphenicol]]||S||S||X1||X1||I||I||I||R||X1||R||R||S
|-
|-
| ||Clarithromycin||+/-||+||||||0||0||+||0||+/-||0||0||+
| ||[[Clindamycin]]||S||S||X1||X1||R||R||S||R||I||R||R||
|-
|-
| Ketolide||Telithromycin||+||+/-||||||+/-||0||+||0||+/-||0||0||+
| [[Macrolides]]||Erythromycin||I||I||X1||X1||R||R||I||R||I||I||R||S
|-
|-
| Tetracyclines||[[Doxycycline]]||+/-||+||||||0||0||+/-||+/-||+||0||0||+
| ||[[Azithromycin]]||I||I||X1||X1||R||R||S||R||I||R||R||S
|-
|-
| ||Minocycline||+||+||||||0||0||+/-||+/-||+||0||0||+
| ||Clarithromycin||I||I||X1||X1||R||R||S||R||I||R||R||S
|-
|-
| Glycylcycline||Tigecycline||+||+||||||+||+||+||+||+||+||+||+
| Ketolide||Telithromycin||S||S||X1||X1||I||R||S||R||I||R||R||S
|-
|-
| Sulfonamides||[[TMP-SMX]]||+||+||||||+||0||+||+||+||+/-||0||+
| Tetracyclines||[[Doxycycline]]||I||S||X1||X1||R||R||I||I||S||R||R||S
|-
|-
| Urinary Agents||[[Nitrofurantoin]]||+||+||||||+||+||+||+||+||||0||
| ||Minocycline||S||S||X1||X1||R||R||S||I||S||R||R||S
|-
|-
| ||Fosfomycin||||||||||+||+/-||||||||||||
| Glycylcycline||Tigecycline||S||S||X1||X1||S||S||S||S||S||S||S||S
|-
|-
| Other||[[Rifampin]]||+||+||||||+/-||0||+||+||+||+||0||+
| ||Daptomycin||S||X4||X1||X1||S||S||S||S||S||S||S||I
|-
|-
| ||[[Metronidazole]]||0||0||||||0||0||0||0||0||0||+||0
| Glyco/Lipoclycopeptides||[[Vancomycin]]||S||S||X1||X1||S||I||S||S||S||S||S||S
|-
|-
| ||Quinupristin-dalfoppristin||+||+||||||0||+||+||+||+||+||+||+
| ||Teicoplanin||S||S||X1||X1||S||I||S||S||S||I||S||S
|-
|-
| ||[[Linezolid]]||+||+||||||+||+||+||+||+||+||+||+
| ||Telavancin||S||S||X1||X1||S||S||S||S||S||S||S||S
|-
|-
| ||Daptomycin||+||+||||||+||+||+||+||+||+||0||+/-
| ||Fusidic Acid||I||I||X1||X1||S||||S||S||S||S||S||X1
|-
|-
| ||Colistimethate||0||0||||||0||0||0||0||0||0||||0
| ||Trimethoprim||S||I||X1||X1||S||R||I||I||S||S||R||S
|-
|-
| ||Telavancin||+||+||||||+||+||+||+||+||+||+||+
| ||[[TMP-SMX]]||X3||S||X1||X1||X3||R||S||S||S||I||R||S
|-
|-
| ||[[Vancomycin]]||+||+||||||+||+/-||+||+||+||+||+||+
| Urinary Agents||[[Nitrofurantoin]]||S||S||X1||X1||S||S||S||S||S||X1||R||X1
|-
| ||Fosfomycin||||S||X1||X1||S||I||S||S||S||X1||X1||R
|-
| Other||[[Rifampin]]||S||S||X1||X1||I||R||S||S||S||S||S||S
|-
| ||[[Metronidazole]]||R||R||X1||X1||R||R||R||R||R||R||R||R
|-
| ||Quinupristin dalfoppristin||S||S||X1||X1||R||S||S||S||S||S||S||S
|-
| ||[[Linezolid]]||S||S||X1||X1||S||S||S||S||S||S||S||S
|-
| ||Colistimethate||R||R||X1||X1||R||R||R||R||R||R||R||R
|}
|}


Revision as of 06:12, 3 June 2014

Gram Positives

Category Organism Strep. Group A, B, C, G Strep. Pneumoniae Viridans strep Strep. anginosus gp Enterococcus faecalis Enterococcus faecium MSSA MRSA CA-MRSA Staph. Epidermidis C. jeikeium L. monocytogenes
Penicillins Penicillin G S S I S S I R R R R R S
Penicillin V S S I S S I R R R R R R
Methicillin S S I S R R S R R S R R
Nafcillin/Oxacillin S S I S R R S R R S R R
Cloxacillin/Diclox. S S I S R R S R R S R R
Amino-Penicillins AMP/Amox S S I S S I R R R R R S
Amox-Clav S S I S S S S R R R R X2
AMP-Sulb S S I S S S S R R R R S
Anti-Pseudomonal Penicillins Ticarcillin S S I S I I R R R I R S
Ticar-Clav S S I S I I S R R I R X2
Pip-Tazo S S I S S I S R R S X1 X2
Piperacillin S S I S S I R R R R R S
Carbapenems Doripenem S S S S I R S R R S X1 S
Ertapenem S S S S R R S R R S R I
Imipenem S S S S S I S R R S R S
Meropenem S S S S I R S R R S X1 S
Aztreonam R R R R R R R R R R R R
Fluroquinolones Ciprofloxacin I I R R ^^ R S R I S R S
Ofloxacin I I R R ^^ R S R X1 S R R
Pefloxacin R R X1 X1 R R S R X1 S X1 R
Levofloxacin S S S S S R S R I S X1 S
Moxifloxacin S S S S S I S I I S X1 S
Gemifloxacin S S S S S I S I I S X1 S
Gatifloxacin S S S S S I S I I S X1 S
1st G Cephalo Cefazolin S S S X1 R X1 S R R I R R
2nd G. Cephalo Cefotetan S S S X1 R X1 S R R I R R
Cefoxitin S S S X1 R X1 S R R I R R
Cefuroxime S S S X1 R X1 S R R I R R
3rd/4th G. Cephalo Cefotaxime S S S X1 R X1 S R R I R R
Cefizoxime S S S X1 R X1 S R R I R R
CefTRIAXone S S S X1 R X1 S R R I R R
Ceftaroline S S S X1 S X1 S S S S X1 X1
CefTAZidime S S I X1 R X1 I R R I R R
Cefepime S S S X1 R X1 S R R I R
Oral 1st G. Cephalo Cefadroxil S S S X1 R X1 S R R I R R
Cephalexin S S S X1 R X1 S R R I R R
Oral 2nd G. Cephalo Cefaclor/Loracarbef S S S X1 R X1 S R R I R R
Cefproxil S S R X1 R X1 S R R I R R
Cefuroxime axetil S S S X1 R X1 S R R I R R
Oral 3rd G. Cephalo Cefixime S S S X1 R X1 R R R R R R
Ceftibuten S I R X1 R X1 R R R R R R
Cefpodox/Cefdinir/Cefditoren S S S X1 R X1 S R R I X1 R
Aminoglycosides Gentamicin R R X1 X1 SS SS S R X1 I R SS
Tobramycin R R X1 X1 SS R S R X1 I R SS
Amikacin R R X1 X1 SS R S R X1 I R SS
Chloramphenicol S S X1 X1 I I I R X1 R R S
Clindamycin S S X1 X1 R R S R I R R
Macrolides Erythromycin I I X1 X1 R R I R I I R S
Azithromycin I I X1 X1 R R S R I R R S
Clarithromycin I I X1 X1 R R S R I R R S
Ketolide Telithromycin S S X1 X1 I R S R I R R S
Tetracyclines Doxycycline I S X1 X1 R R I I S R R S
Minocycline S S X1 X1 R R S I S R R S
Glycylcycline Tigecycline S S X1 X1 S S S S S S S S
Daptomycin S X4 X1 X1 S S S S S S S I
Glyco/Lipoclycopeptides Vancomycin S S X1 X1 S I S S S S S S
Teicoplanin S S X1 X1 S I S S S I S S
Telavancin S S X1 X1 S S S S S S S S
Fusidic Acid I I X1 X1 S S S S S S X1
Trimethoprim S I X1 X1 S R I I S S R S
TMP-SMX X3 S X1 X1 X3 R S S S I R S
Urinary Agents Nitrofurantoin S S X1 X1 S S S S S X1 R X1
Fosfomycin S X1 X1 S I S S S X1 X1 R
Other Rifampin S S X1 X1 I R S S S S S S
Metronidazole R R X1 X1 R R R R R R R R
Quinupristin dalfoppristin S S X1 X1 R S S S S S S S
Linezolid S S X1 X1 S S S S S S S S
Colistimethate R R X1 X1 R R R R R R R R

Gram Negatives

Category Antibiotic N. gonorrhoeae
Penicillins Penicillin G 0
Penicillin V 0
Anti-Staphylocccal Penicillins Methicillin 0
Nafcillin/Oxacillin 0
Dicloxacillin 0
Amino-Penicillins AMP/Amox 0
Amox-Clav +
AMP-Sulb +
Anti-Pseudomonal Penicillins Ticar-Clav +
Pip-Tazo +
Carbapenems Doripenem +
Ertapenem +
Imipenem +
Meropenem +
Monobactam Aztreonam +
Fluroquinolones Ciprofloxacin +*
Ofloxacin +*
Levofloxacin +*
Moxifloxacin +*
Gemifloxacin
Gatifloxacin +*
1st G Cephalo Cefazolin +
2nd G Cephalo Cefotetan +/-
Cefoxitin +/-
Cefuroxime +/-
3rd/4th G Cephalo Cefotaxime +/-
Cefizoxime +/-
CefTRIAXone +
Ceftaroline +
CefTAZidime +/-
Cefepime +
Oral 1st G Cephalo Cefadroxil 0
Cephalexin 0
Oral 2nd G Cephalo Cefaclor +/-
Cefproxil +/-
Cefuroxime +/-
Oral 3rd G Cephalo Cefixime +
Ceftibuten +/-
Cefpodox/ Cefdinir/ Cefditoren +
Aminoglycosides Gentamicin 0
Tobramycin 0
Amikacin 0
Chloramphenicol +
Clindamycin 0
Macrolides Erythromycin +/-
Azithromycin +/-
Clarithromycin +/-
Ketolide Telithromycin +
Tetracyclines Doxycycline +/-
Minocycline +/-
Glycylcycline Tigecycline +
Sulfonamides TMP-SMX +/-
Urinary Agents Nitrofurantoin +
Fosfomycin +
Other Rifampin +
Metronidazole 0
Quinupristin-dalfoppristin +
Linezolid
Daptomycin 0
Colistimethate 0
Telavancin 0
Vancomycin 0

Key

  • + usually effective clinically or >60% susceptible
  • +/- clinical trials lacking or 30-60% susceptible
  • 0 not effective clinically or <30% susceptible
  • blank data not available
Gram Positives
Cocci
Clusters
Pairs/Chains
Other
Rods
Gram Negatives
Cocci
Rods
Lactose Fermenters
Lactose Non-Fermenters
Other
Rods/Cocci
Anaerobes
Clinically Utilized Antibiotics
β-lactams
Natural
Anti-Staphylococcal
Amino-Penicillins
Anti-Pseudomonal
1st
2nd
3rd
4th (antipseudomonal)
5th
Monobactams
Aminoglycosides
-mycin (Streptomyces)
-micin (Micromonospora)
Tetracyclines
Tetracyclines
Glycylcyclines
Macrolides
Standard
Ketolide
Sulfonamides
  • TMP-SMX (Bactrim)
    • Urinary Tract Agents
    Fluroquinolones
    2nd g.
    3rd g.
    4th g.
    Other

    See Also

    Source

    • Sanford Guide to Antimicrobial Therapy 2010
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